Giovana da Silva Leandro
Overview
Explore the profile of Giovana da Silva Leandro including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
22
Followers
0
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Recent Articles
1.
Mendes I, Dos Reis Bertoldo W, Miranda-Junior A, de Assis A, Repoles B, Rodrigues Ferreira W, et al.
DNA Repair (Amst)
. 2024 Aug;
141:103726.
PMID: 39096697
Trypanosoma cruzi is the etiological agent of Chagas disease and a peculiar eukaryote with unique biological characteristics. DNA damage can block RNA polymerase, activating transcription-coupled nucleotide excision repair (TC-NER), a...
2.
Latancia M, da Silva Leandro G, Bastos A, Moreno N, Ariwoola A, Martins D, et al.
DNA Repair (Amst)
. 2024 Jul;
141:103715.
PMID: 39029375
Glioblastoma (GBM) is a highly aggressive brain tumor associated with poor patient survival. The current standard treatment involves invasive surgery, radiotherapy, and chemotherapy employing temozolomide (TMZ). Resistance to TMZ is,...
3.
Martins D, Singh J, Jahjah T, Vessoni A, da Silva Leandro G, Silva M, et al.
Photochem Photobiol
. 2023 Nov;
100(1):4-18.
PMID: 37926965
Xeroderma pigmentosum (XP) variant cells are deficient in the translesion synthesis (TLS) DNA polymerase Polη (eta). This protein contributes to DNA damage tolerance, bypassing unrepaired UV photoproducts and allowing S-phase...
4.
Schavinski C, Santos M, Londero J, Rocha M, do Amaral A, Ruiz N, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2022 Dec;
883-884:503549.
PMID: 36462791
The biodiversity collapse strongly affects the amphibian group and many factors have been pointed out as catalytic agents. It is estimated that several events in the amphibian population decline worldwide...
5.
Lima K, Pereira-Martins D, de Miranda L, Coelho-Silva J, da Silva Leandro G, Weinhauser I, et al.
Blood Cancer J
. 2022 Nov;
12(11):151.
PMID: 36347832
The treatment of acute leukemia is challenging because of the genetic heterogeneity between and within patients. Leukemic stem cells (LSCs) are relatively drug-resistant and frequently relapse. Their plasticity and capacity...
6.
Transcription blockage by DNA damage in nucleotide excision repair-related neurological dysfunctions
Kajitani G, Nascimento L, Neves M, da Silva Leandro G, Garcia C, Menck C
Semin Cell Dev Biol
. 2020 Nov;
114:20-35.
PMID: 33229217
Human genetic syndromes deficient in nucleotide excision repair (NER), such as xeroderma pigmentosum and Cockayne syndrome, may present neurological abnormalities and premature aging symptoms. Unrepaired endogenously generated DNA damage that...