Giorgio Turconi
Overview
Explore the profile of Giorgio Turconi including associated specialties, affiliations and a list of published articles.
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8
Citations
84
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Recent Articles
1.
Turconi G, Alam F, SenGupta T, Pirnes-Karhu S, Olfat S, Schmidt M, et al.
Heliyon
. 2024 Aug;
10(14):e34355.
PMID: 39108921
Parkinson's disease (PD) is associated with a reduction in 26/20S proteasome and mitochondrial function and depletion of dopamine. Activation of mitochondrial function with the NAD precursor nicotinamide riboside (NR) is...
2.
Garton D, Turconi G, Iivanainen V, Andressoo J
Biomolecules
. 2023 May;
13(5).
PMID: 37238631
Cocaine addiction is a serious condition with potentially lethal complications and no current pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine system are crucial to the establishment of cocaine-induced...
3.
Lekk I, Cabrera-Cabrera F, Turconi G, Tuvikene J, Esvald E, Rahni A, et al.
J Biol Chem
. 2023 Jan;
299(2):102897.
PMID: 36639028
Brain-derived neurotrophic factor (BDNF) promotes neuronal survival and growth during development. In the adult nervous system, BDNF is important for synaptic function in several biological processes such as memory formation...
4.
Matlik K, Garton D, Montano-Rodriguez A, Olfat S, Eren F, Casserly L, et al.
Mol Psychiatry
. 2022 May;
27(8):3247-3261.
PMID: 35618883
Presynaptic increase in striatal dopamine is the primary dopaminergic abnormality in schizophrenia, but the underlying mechanisms are not understood. Here, we hypothesized that increased expression of endogenous GDNF could induce...
5.
Mitra S, Turconi G, Darreh-Shori T, Matlik K, Aquilino M, Eriksdotter M, et al.
Front Aging Neurosci
. 2021 Sep;
13:714186.
PMID: 34475820
Gradual decline in cholinergic transmission and cognitive function occurs during normal aging, whereas pathological loss of cholinergic function is a hallmark of different types of dementia, including Alzheimer's disease (AD),...
6.
Turconi G, Kopra J, Voikar V, Kulesskaya N, Vilenius C, Piepponen T, et al.
Mol Ther Methods Clin Dev
. 2020 May;
17:831-842.
PMID: 32368564
Glial cell line-derived neurotrophic factor (GDNF) supports function and survival of dopamine neurons that degenerate in Parkinson's disease (PD). Ectopic delivery of GDNF in clinical trials to treat PD is...
7.
Danesi C, Achuta V, Corcoran P, Peteri U, Turconi G, Matsui N, et al.
Stem Cell Reports
. 2018 Dec;
11(6):1449-1461.
PMID: 30503263
The absence of FMR1 protein (FMRP) causes fragile X syndrome (FXS) and disturbed FMRP function is implicated in several forms of human psychopathology. We show that intracellular calcium responses to...
8.
Achuta V, Moykkynen T, Peteri U, Turconi G, Rivera C, Keinanen K, et al.
Sci Signal
. 2018 Jan;
11(513).
PMID: 29339535
Altered neuronal network formation and function involving dysregulated excitatory and inhibitory circuits are associated with fragile X syndrome (FXS). We examined functional maturation of the excitatory transmission system in FXS...