Gina La Sala
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Explore the profile of Gina La Sala including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
278
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Recent Articles
1.
Lacconi V, Massimiani M, Antonello G, Gasco P, Bernardini R, Ferrari C, et al.
Front Toxicol
. 2025 Jan;
6():1508598.
PMID: 39839550
Solid lipid nanoparticles (SLNs) have gained interest as drug delivery carriers due to their efficient cellular internalization and increased therapeutic effect of the loaded drug, with minimal side effects. Although...
2.
Russo B, DAddato G, Salvatore G, Menduni M, Frontoni S, Carbone L, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684590
Retinal neurodegeneration (RN), an early marker of diabetic retinopathy (DR), is closely associated with Müller glia cells (MGs) in diabetic subjects. MGs play a pivotal role in maintaining retinal homeostasis,...
3.
Guerra M, Medici V, La Sala G, Farini D
Cells
. 2024 Jul;
13(14.
PMID: 39056758
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social interaction and communication, as well as repetitive behaviors. Although the etiology of ASD is multifactorial, with both...
4.
Pasquini M, Chiani F, Gambadoro A, Di Pietro C, Paoletti R, Orsini T, et al.
Cells
. 2024 Jun;
13(12.
PMID: 38920681
gene loss-of-function mutation leads to Primary Ciliary Dyskinesia (PCD), a disease caused by motile cilia dysfunction. Previously, we demonstrated that knockout of the gene in mice replicates several features of...
5.
Massimi M, Di Pietro C, La Sala G, Matteoni R
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457105
The vertebrate G protein-coupled receptor 37 and G protein-coupled receptor 37-like 1 (GPR37 and GPR37L1) proteins have amino acid sequence homology to endothelin and bombesin-specific receptors. The prosaposin glycoprotein, its...
6.
Cocola C, Magnaghi V, Abeni E, Pelucchi P, Martino V, Vilardo L, et al.
Front Cell Neurosci
. 2021 Dec;
15:703431.
PMID: 34867197
Glioblastomas (GBM) are the most aggressive tumors originating in the brain. Histopathologic features include circuitous, disorganized, and highly permeable blood vessels with intermittent blood flow. These features contribute to the...
7.
Alonso-Gardon M, Elorza-Vidal X, Castellanos A, La Sala G, Armand-Ugon M, Gilbert A, et al.
Hum Mol Genet
. 2021 Jun;
30(17):1649-1665.
PMID: 34100078
Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a type of vacuolating leukodystrophy, which is mainly caused by mutations in MLC1 or GLIALCAM. The two MLC-causing genes encode for membrane proteins...
8.
La Sala G, Di Pietro C, Matteoni R, Bolasco G, Marazziti D, Tocchini-Valentini G
J Neurosci Res
. 2020 Dec;
PMID: 33350496
Mammalian cerebellar astrocytes critically regulate the differentiation and maturation of neuronal Purkinje cells and granule precursors. The G protein-coupled receptor 37-like 1 (Gpr37l1) is expressed by Bergmann astrocytes and interacts...
9.
Farini D, Cesari E, Weatheritt R, La Sala G, Naro C, Pagliarini V, et al.
Cell Rep
. 2020 Jun;
31(9):107703.
PMID: 32492419
Tight coordination of gene expression in the developing cerebellum is crucial for establishment of neuronal circuits governing motor and cognitive function. However, transcriptional changes alone do not explain all of...
10.
Lucarelli M, Di Pietro C, La Sala G, Fiorenza M, Marazziti D, Canterini S
Front Cell Neurosci
. 2019 Jun;
13:226.
PMID: 31178699
The Niemann-Pick type C1 (NPC1) is a rare genetic disease characterized by the accumulation of endocytosed cholesterol and other lipids in the endosome/lysosome compartments. In the brain, the accumulation/mislocalization of...