Gillian P McHugo
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Explore the profile of Gillian P McHugo including associated specialties, affiliations and a list of published articles.
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54
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Recent Articles
1.
McHugo G, Ward J, Nganga S, Frantz L, Salter-Townshend M, Hill E, et al.
Heredity (Edinb)
. 2024 Nov;
134(1):49-63.
PMID: 39516247
Bos taurus (taurine) and Bos indicus (indicine) cattle diverged at least 150,000 years ago and, since that time, substantial genomic differences have evolved between the two lineages. During the last...
2.
Kelly P, McHugo G, Scaife C, Peters S, Stevenson M, McKay J, et al.
Parasite Immunol
. 2024 Apr;
46(4):e13033.
PMID: 38607285
Canine demodicosis is a prevalent skin disease caused by overpopulation of a commensal species of Demodex mite, yet its precise cause remains unknown. Research suggests that T-cell exhaustion, increased immunosuppressive...
3.
Ward J, Nganga S, Randhawa I, McHugo G, OGrady J, Florez J, et al.
R Soc Open Sci
. 2024 Apr;
11(3):231388.
PMID: 38571912
Criollo cattle, the descendants of animals brought by Iberian colonists to the Americas, have been the subject of natural and human-mediated selection in novel tropical agroecological zones for centuries. Consequently,...
4.
Hall T, McHugo G, Mullen M, Ward J, Killick K, Browne J, et al.
Tuberculosis (Edinb)
. 2023 Dec;
147:102453.
PMID: 38071177
Mycobacterium tuberculosis, the causative agent of human tuberculosis (hTB), is a close evolutionary relative of Mycobacterium bovis, which causes bovine tuberculosis (bTB), one of the most damaging infectious diseases to...
5.
Bhat S, Elnaggar M, Hall T, McHugo G, Reid C, MacHugh D, et al.
Front Immunol
. 2023 Nov;
14:1265038.
PMID: 37942326
Bovine tuberculosis (bTB), caused by infection with , continues to cause significant issues for the global agriculture industry as well as for human health. An incomplete understanding of the host...
6.
Correia C, McHugo G, Browne J, McLoughlin K, Nalpas N, Magee D, et al.
Tuberculosis (Edinb)
. 2022 Aug;
136:102235.
PMID: 35952489
Objectives: Improved bovine tuberculosis (bTB) diagnostics with higher sensitivity and specificity are urgently required. A better understanding of the peripheral blood transcriptional response of Mycobacterium bovis-infected animals after bovine purified...
7.
Ward J, McHugo G, Dover M, Hall T, Nganga S, Sonstegard T, et al.
iScience
. 2022 Jul;
25(7):104672.
PMID: 35832892
The phenotypic diversity of African cattle reflects adaptation to a wide range of agroecological conditions, human-mediated selection preferences, and complex patterns of admixture between the humpless (taurine) and humped (zebu)...
8.
Hall T, Mullen M, McHugo G, Killick K, Ring S, Berry D, et al.
BMC Genomics
. 2021 May;
22(1):343.
PMID: 33980141
Background: Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a major endemic disease affecting global cattle production. The key innate immune cell that first encounters the pathogen is...
9.
McHugo G, Dover M, MacHugh D
BMC Biol
. 2019 Dec;
17(1):98.
PMID: 31791340
Animal domestication has fascinated biologists since Charles Darwin first drew the parallel between evolution via natural selection and human-mediated breeding of livestock and companion animals. In this review we show...
10.
McHugo G, Browett S, Randhawa I, Howard D, Mullen M, Richardson I, et al.
Front Genet
. 2019 Oct;
10:927.
PMID: 31649720
The Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as 'at-risk'. In the present study, comparative population genomics analyses of...