Giel Vandemoortele
Overview
Explore the profile of Giel Vandemoortele including associated specialties, affiliations and a list of published articles.
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8
Citations
68
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Recent Articles
1.
Vandemoortele G, De Sutter D, Eyckerman S
Bio Protoc
. 2021 Sep;
7(7):e2211.
PMID: 34541219
The programmable Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated nuclease 9 (Cas9) technology revolutionized genome editing by providing an efficient way to cut the genome at a desired location (Ledford,...
2.
Vandemoortele G, Eyckerman S, Gevaert K
Trends Biotechnol
. 2019 May;
37(10):1078-1090.
PMID: 31036349
Protein tags have been essential for advancing our knowledge of the function of proteins, their localization, and the mapping of their interaction partners. Expressing epitope-tagged proteins has become a standard...
3.
Vandemoortele G, De Sutter D, Moliere A, Pauwels J, Gevaert K, Eyckerman S
J Proteome Res
. 2018 Dec;
18(1):95-106.
PMID: 30525648
The CRISPR/Cas9 revolution is profoundly changing the way life sciences technologies are used. Many assays now rely on engineered clonal cell lines to eliminate the overexpression of bait proteins. Control...
4.
Masschaele D, Wauman J, Vandemoortele G, De Sutter D, De Ceuninck L, Eyckerman S, et al.
J Proteome Res
. 2018 Mar;
17(4):1348-1360.
PMID: 29560723
Ring finger protein 41 (RNF41) is an E3 ubiquitin ligase involved in the ubiquitination and degradation of many proteins including ErbB3 receptors, BIRC6, and parkin. Next to this, RNF41 regulates...
5.
Eyckerman S, Impens F, Van Quickelberghe E, Samyn N, Vandemoortele G, De Sutter D, et al.
J Proteome Res
. 2016 Sep;
15(10):3929-3937.
PMID: 27640904
Protein complexes are essential in all organizational and functional aspects of the cell. Different strategies currently exist for analyzing such protein complexes by mass spectrometry, including affinity purification (AP-MS) and...
6.
Vandemoortele G, Staes A, Gonnelli G, Samyn N, De Sutter D, Vandermarliere E, et al.
Sci Rep
. 2016 Jun;
6:27220.
PMID: 27264994
The use of protein tagging to facilitate detailed characterization of target proteins has not only revolutionized cell biology, but also enabled biochemical analysis through efficient recovery of the protein complexes...
7.
Vandemoortele G, Gevaert K, Eyckerman S
Proteomics
. 2015 Oct;
16(2):177-87.
PMID: 26510734
Genome engineering experiments used to be lengthy, inefficient, and often expensive, preventing a widespread adoption of such experiments for the full assessment of endogenous protein functions. With the revolutionary clustered...
8.
Van Damme P, Plasman K, Vandemoortele G, Jonckheere V, Maurer-Stroh S, Gevaert K
BMC Biochem
. 2014 Sep;
15:21.
PMID: 25208769
Background: Previous screening of the substrate repertoires and substrate specificity profiles of granzymes resulted in long substrate lists highly likely containing bystander substrates. Here, a recently developed degradomics technology that...