Giedrius Steponaitis
Overview
Explore the profile of Giedrius Steponaitis including associated specialties, affiliations and a list of published articles.
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20
Citations
219
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Recent Articles
1.
Sirvinskas D, Steponaitis G, Stakaitis R, Tamasauskas A, Vaitkiene P, Skiriute D
Front Mol Biosci
. 2023 Mar;
10:1101953.
PMID: 36950523
Natural non-coding antisense transcripts (ncNATs) are long non-coding RNAs (lncRNA) transcribed from the opposite strand of a separate protein coding or non-coding gene. As such, ncNATs can increase overlapping mRNA...
2.
Krusnauskas R, Stakaitis R, Steponaitis G, Almstrup K, Vaitkiene P
Epigenetics
. 2023 Jan;
18(1):2163365.
PMID: 36597408
The most prominent RNA modification - N6-methyladenosine (m6A) - affects gene regulation and cancer progression. The extent and effect of m6A on long non-coding RNAs (lncRNAs) is, however, still not...
3.
Steponaitis G, Kucinskas V, Golubickaite I, Skauminas K, Saudargiene A
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555518
Most glioblastoma studies incorporate the layer of tumor molecular subtype based on the four-subtype classification system proposed in 2010. Nevertheless, there is no universally recognized and convenient tool for glioblastoma...
4.
Steponaitis G, Stakaitis R, Valiulyte I, Krusnauskas R, Dragunaite R, Urbanaviciute R, et al.
Sci Rep
. 2022 Apr;
12(1):5431.
PMID: 35361860
The interest in chemical RNA modifications is rapidly growing in the field of molecular biology. Dynamic and reversible alterations of N6-methyladenosine (m6A) RNA modification are responsible for a platter of...
5.
Kulakauskiene D, Narauskaite D, Gecys D, Juknaite O, Jankauskaite L, Masaityte A, et al.
Biology (Basel)
. 2021 Dec;
10(12).
PMID: 34943274
Viral infections induce extracellular vesicles (EVs) containing viral material and inflammatory factors. Exosomes can easily cross the blood-brain barrier during respiratory tract infection and transmit the inflammatory signal to the...
6.
Steponaitis G, Tamasauskas A
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34066996
Glioblastomas (GBM)-the most common, therapy-resistant, and lethal tumors driven by populations of glioma stem cells (GSCs) are still on the list of the most complicated pathologies. Thus, deeper understanding and...
7.
Skiriute D, Stakaitis R, Steponaitis G, Tamasauskas A, Vaitkiene P
Int J Mol Sci
. 2020 Oct;
21(21).
PMID: 33120918
Recently long non-coding RNAs (lncRNAs) were highlighted for their regulatory role in tumor biology. The novel human lncRNA cancer susceptibility candidate 2 () has been characterized as a potential tumor...
8.
Stakaitis R, Pranckeviciene A, Steponaitis G, Tamasauskas A, Bunevicius A, Vaitkiene P
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33050332
In the last decade, an increasing amount of research has been conducted analyzing microRNA expression changes in glioma tissue and its expressed exosomes, but there is still sparse information on...
9.
Valiulyte I, Steponaitis G, Kardonaite D, Tamasauskas A, Kazlauskas A
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33036421
Glioma is a lethal central nervous system tumor with poor patient survival prognosis. Because of the molecular heterogeneity, it is a challenge to precisely determine the type of the tumor...
10.
Sinceviciute R, Vaitkiene P, Urbanaviciute R, Steponaitis G, Tamasauskas A, Skiriute D
Int J Clin Exp Pathol
. 2020 Jan;
11(6):3010-3018.
PMID: 31938426
Gliomas are fast growing and usually manifest in an aggressive infiltrative model. overexpression is associated with brain tumor malignancy and metastasis formation. The aim of this study was to investigate...