Giedrius Gasiunas
Overview
Explore the profile of Giedrius Gasiunas including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
2946
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Recent Articles
1.
Pudziuvelyte I, Olechnovic K, Godliauskaite E, Sermokas K, Urbaitis T, Gasiunas G, et al.
Bioinformatics
. 2024 Mar;
40(4).
PMID: 38507682
Motivation: Reliable prediction of protein thermostability from its sequence is valuable for both academic and industrial research. This prediction problem can be tackled using machine learning and by taking advantage...
2.
Cavazza A, Hendel A, Bak R, Rio P, Guell M, Lainscek D, et al.
Mol Ther Nucleic Acids
. 2023 Nov;
34:102066.
PMID: 38034032
The European Cooperation in Science and Technology (COST) is an intergovernmental organization dedicated to funding and coordinating scientific and technological research in Europe, fostering collaboration among researchers and institutions across...
3.
Uludag H, Montazeri Aliabadi H, Gasiunas G
Front Bioeng Biotechnol
. 2022 Dec;
10:1103007.
PMID: 36568287
No abstract available.
4.
Urbaitis T, Gasiunas G, Young J, Hou Z, Paulraj S, Godliauskaite E, et al.
EMBO Rep
. 2022 Oct;
23(12):e55481.
PMID: 36268581
Most CRISPR-type V nucleases are stimulated to cleave double-stranded (ds) DNA targets by a T-rich PAM, which restricts their targeting range. Here, we identify and characterize a new family of...
5.
Balderston S, Clouse G, Ripoll J, Pratt G, Gasiunas G, Bock J, et al.
CRISPR J
. 2021 Jun;
4(3):400-415.
PMID: 34152221
The discovery of CRISPR has revolutionized the field of genome engineering, but the potential of this technology is far from reaching its limits. In this review, we explore the broad...
6.
Balderston S, Taulbee J, Celaya E, Fung K, Jiao A, Smith K, et al.
Nat Biomed Eng
. 2021 Apr;
5(7):713-725.
PMID: 33820980
Simple and fast methods for the detection of target genes with single-nucleotide specificity could open up genetic research and diagnostics beyond laboratory settings. We recently reported a biosensor for the...
7.
Gasiunas G, Young J, Karvelis T, Kazlauskas D, Urbaitis T, Jasnauskaite M, et al.
Nat Commun
. 2020 Nov;
11(1):5512.
PMID: 33139742
Bacterial Cas9 nucleases from type II CRISPR-Cas antiviral defence systems have been repurposed as genome editing tools. Although these proteins are found in many microbes, only a handful of variants...
8.
Mullally G, van Aelst K, Naqvi M, Diffin F, Karvelis T, Gasiunas G, et al.
Nucleic Acids Res
. 2020 Jun;
48(12):6811-6823.
PMID: 32496535
A key aim in exploiting CRISPR-Cas is gRNA engineering to introduce additional functionalities, ranging from individual nucleotide changes that increase efficiency of on-target binding to the inclusion of larger functional...
9.
Wilkinson M, Drabavicius G, Silanskas A, Gasiunas G, Siksnys V, Wigley D
Mol Cell
. 2019 May;
75(1):90-101.e5.
PMID: 31080012
CRISPR and associated Cas proteins function as an adaptive immune system in prokaryotes to combat bacteriophage infection. During the immunization step, new spacers are acquired by the CRISPR machinery, but...
10.
Sulcius S, Simoliunas E, Alzbutas G, Gasiunas G, Jauniskis V, Kuznecova J, et al.
Appl Environ Microbiol
. 2018 Oct;
85(1).
PMID: 30367000
While filamentous cyanobacteria play a crucial role in food web dynamics and biogeochemical cycling of many aquatic ecosystems around the globe, the knowledge regarding the phages infecting them is limited....