Gianfranco Volpini
Overview
Explore the profile of Gianfranco Volpini including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
397
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0
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Recent Articles
1.
Siena E, Schiavetti F, Borgogni E, Taccone M, Faenzi E, Brazzoli M, et al.
Vaccine
. 2022 Dec;
41(3):724-734.
PMID: 36564274
The candidate Adjuvant System AS37 contains a synthetic toll-like receptor agonist (TLR7a) adsorbed to alum. In a phase I study (NCT02639351), healthy adults were randomised to receive one dose of...
2.
Budroni S, Buricchi F, Cavallone A, Volpini G, Mariani A, Lo Surdo P, et al.
Comput Struct Biotechnol J
. 2021 Jul;
19:3664-3672.
PMID: 34257845
Affinity measurement is a fundamental step in the discovery of monoclonal antibodies (mAbs) and of antigens suitable for vaccine development. Innovative affinity assays are needed due to the low throughput...
3.
Budroni S, Buricchi F, Cavallone A, Bourguignon P, Caubet M, Dewar V, et al.
NPJ Vaccines
. 2021 May;
6(1):78.
PMID: 34021167
Differences in innate immune 'imprinting' between vaccine adjuvants may mediate dissimilar effects on the quantity/quality of persisting adaptive responses. We compared antibody avidity maturation, antibody/memory B cell/CD4 T cell response...
4.
Leroux-Roels G, Lattanzi M, Solis C, Contorni M, Costantini M, Moraschini L, et al.
Hum Vaccin Immunother
. 2017 Nov;
14(1):45-58.
PMID: 29172945
Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries. This randomized, controlled, observer-blind phase I study and extension study in Belgium (March 2012-June 2015) assessed safety and immunogenicity...
5.
Faleri A, Santini L, Brier S, Pansegrau W, Lo Surdo P, Scarselli M, et al.
FASEB J
. 2013 Dec;
28(4):1644-53.
PMID: 24371123
Factor H binding protein (fHbp) is one of the main antigens of the 4-component meningococcus B (4CMenB) multicomponent vaccine against disease caused by serogroup B Neisseria meningitidis (MenB). fHbp binds...
6.
Spensieri F, Borgogni E, Zedda L, Bardelli M, Buricchi F, Volpini G, et al.
Proc Natl Acad Sci U S A
. 2013 Aug;
110(35):14330-5.
PMID: 23940329
Protection against influenza is mediated by neutralizing antibodies, and their induction at high and sustained titers is key for successful vaccination. Optimal B cells activation requires delivery of help from...
7.
Faenzi E, Zedda L, Bardelli M, Spensieri F, Borgogni E, Volpini G, et al.
Vaccine
. 2012 Apr;
30(27):4086-94.
PMID: 22521851
Protective antibody responses to a single dose of 2009 pandemic vaccines have been observed in the majority of healthy subjects aged more than 3 years. These findings suggest that immune...
8.
Gallorini S, Berti F, Mancuso G, Cozzi R, Tortoli M, Volpini G, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(41):17481-6.
PMID: 19805031
Group B Streptococcus (GBS) causes serious infection in neonates and is an important target of vaccine development. Zwitterionic polysaccharides (ZPS), obtained through chemical introduction of positive charges into anionic polysaccharides...
9.
Galli G, Pittoni P, Tonti E, Malzone C, Uematsu Y, Tortoli M, et al.
Proc Natl Acad Sci U S A
. 2007 Mar;
104(10):3984-9.
PMID: 17360464
Invariant natural killer T (iNKT) cells are innate-like lymphocytes recognizing CD1d-restricted glycolipid antigens, such as alpha-galactosylceramide (alphaGC). We assessed whether iNKT cells help B lymphocyte responses and found that mice...
10.
Buccato S, Maione D, Rinaudo C, Volpini G, Taddei A, Rosini R, et al.
J Infect Dis
. 2006 Jul;
194(3):331-40.
PMID: 16826481
Recent data indicate that the human pathogen group B Streptococcus (GBS) produces pilus-like structures encoded in genomic islands with similar organization to pathogenicity islands. On the basis of the amino...