Gian C Gazzola
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Explore the profile of Gian C Gazzola including associated specialties, affiliations and a list of published articles.
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17
Citations
263
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Recent Articles
1.
Barilli A, Rotoli B, Visigalli R, Bussolati O, Gazzola G, Gatti R, et al.
Mol Genet Metab
. 2012 Feb;
105(4):585-9.
PMID: 22325938
Lysinuric Protein Intolerance (LPI, MIM 222700) is a recessive aminoaciduria caused by defective cationic amino acid transport in epithelial cells of intestine and kidney. SLC7A7, the gene mutated in LPI,...
2.
Barilli A, Rotoli B, Visigalli R, Bussolati O, Gazzola G, DallAsta V
J Leukoc Biol
. 2011 May;
90(2):293-303.
PMID: 21586674
L-arginine metabolism in myeloid cells plays a central role in the processes of macrophage activation and in the regulation of immune responses. In this study, we investigated arginine transport activity...
3.
Barilli A, Rotoli B, Visigalli R, Bussolati O, Gazzola G, Kadija Z, et al.
Orphanet J Rare Dis
. 2010 Nov;
5:32.
PMID: 21110863
Background: In the recessive aminoaciduria Lysinuric Protein Intolerance (LPI), mutations of SLC7A7/y+LAT1 impair system y+L transport activity for cationic amino acids. A severe complication of LPI is a form of...
4.
Visigalli R, Barilli A, Parolari A, Sala R, Rotoli B, Bussolati O, et al.
J Mol Cell Cardiol
. 2010 May;
49(2):260-70.
PMID: 20430034
Endothelial metabolism of arginine plays a key role in vascular homeostasis. While it is documented that the availability of extracellular arginine is critical for nitric oxide synthesis by eNOS, little...
5.
Rotoli B, Closs E, Barilli A, Visigalli R, Simon A, Habermeier A, et al.
Pflugers Arch
. 2009 Jun;
458(6):1163-73.
PMID: 19562367
Since arginine metabolites, such as nitric oxide and polyamines, influence the expression of genes involved in erythroid differentiation, the transport of the cationic amino acid may play an important role...
6.
Bianchi M, Gazzola G, Cagnin S, Kagechika H, Bussolati O
Biochim Biophys Acta
. 2009 May;
1788(9):1861-8.
PMID: 19450544
The mechanisms underlying trafficking and membrane targeting of EAAC1, the rodent counterpart of the human EAAT3 carrier for anionic amino acids, are well characterized. In contrast, much less is known...
7.
Barilli A, Visigalli R, Sala R, Gazzola G, Parolari A, Tremoli E, et al.
Cardiovasc Res
. 2008 Feb;
78(3):563-71.
PMID: 18250144
Aim: Drug-eluting stents are widely used to prevent restenosis but are associated with late endothelial damage. To understand the basis for this effect, we have studied the consequences of a...
8.
Visigalli R, Barilli A, Bussolati O, Sala R, Gazzola G, Parolari A, et al.
Biochim Biophys Acta
. 2007 Apr;
1768(6):1479-87.
PMID: 17397797
In endothelial cells Tumor Necrosis Factor-alpha (TNFalpha) stimulates arginine transport through the increased expression of SLC7A2/CAT2 transcripts. Here we show that also rapamycin, an inhibitor of mTOR kinase, stimulates system...
9.
Rotoli B, DallAsta V, Barilli A, DIppolito R, Tipa A, Olivieri D, et al.
Am J Respir Cell Mol Biol
. 2007 Mar;
37(1):105-12.
PMID: 17363779
Systems y+ and y+L represent the main routes for arginine transport in mammalian cells. While system y+ activity is needed for the stimulated NO production in rodent alveolar macrophages (AM),...
10.
Bianchi M, Rotoli B, DallAsta V, Gazzola G, Gatti R, Bussolati O
Neurochem Int
. 2006 Jan;
48(5):341-9.
PMID: 16417946
The activity and the membrane expression of EAAT3 glutamate transporter are stimulated upon PKC activation by phorbol esters in C6 rat glioma cells. To investigate the role of cytoskeleton in...