Giada Botti
Overview
Explore the profile of Giada Botti including associated specialties, affiliations and a list of published articles.
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12
Citations
52
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Recent Articles
1.
Serri C, Piccioni M, Guarino V, Santonicola P, Cruz-Maya I, Crispi S, et al.
Int J Nanomedicine
. 2025 Jan;
20():71-89.
PMID: 39802381
Purpose: Dimethyl fumarate (DMF), the first-line oral therapy for relapsing-remitting multiple sclerosis, is rapidly metabolized into monomethyl fumarate. The DMF oral administration provokes gastrointestinal discomfort causing treatment withdrawal. The present...
2.
Spigarelli R, Spisni E, Magalhaes M, Cabral C, Goncalves A, Saracino I, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796096
This study aimed to investigate β-Caryophyllene (BCA) pharmacokinetics as well as the potential antitumor activity and mechanism of action of BCA and eugenol (EU), alone or in combination, in U87...
3.
Faiella M, Botti G, Dalpiaz A, Gnudi L, Goyenvalle A, Pavan B, et al.
Pharmaceutics
. 2024 Aug;
16(8).
PMID: 39204368
Delivery represents a major hurdle to the clinical advancement of oligonucleotide therapeutics for the treatment of disorders such as Duchenne muscular dystrophy (DMD). In this preliminary study, we explored the...
4.
Albertini B, Bertoni S, Nucci G, Botti G, Abrami M, Sangiorgi S, et al.
Int J Pharm
. 2024 Jul;
661:124417.
PMID: 38964489
Benznidazole (BNZ) serves as the primary drug for treating Chagas Disease and is listed in the WHO Model List of Essential Medicines for Children. Herein, a new child-friendly oral BNZ...
5.
Lerin L, Botti G, Dalpiaz A, Bianchi A, Ferraro L, Chaibi C, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892454
Ferulic acid (Fer) and geraniol (Ger) are natural compounds whose antioxidant and anti-inflammatory activity confer beneficial properties, such as antibacterial, anticancer, and neuroprotective effects. However, the short half-lives of these...
6.
Botti G, Bianchi A, Dalpiaz A, Tedeschi P, Albanese V, Sorrenti M, et al.
Expert Opin Drug Deliv
. 2023 Nov;
20(11):1657-1679.
PMID: 38014509
Objective: Ferulic acid (Fer) displays antioxidant/anti-inflammatory properties useful against neurodegenerative diseases. To increase Fer uptake and its central nervous system residence time, a dimeric prodrug, optimizing the Fer loading on...
7.
Pavan B, Bianchi A, Botti G, Ferraro L, Valerii M, Spisni E, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36675321
Eugenol, cinnamaldehyde and D-limonene, the main components of natural essential oils, are endowed with antioxidant and anti-inflammatory properties which allow them to induce beneficial effects on intestinal, cardiac and neuronal...
8.
Pavan B, Bianchi A, Botti G
iScience
. 2022 Nov;
25(12):105477.
PMID: 36387022
New evidence is emerging about the dynamics of interaction between circadian rhythms and brain waves, whose coordination occurs through the entrainment process. The so-called "oscillopathies" or dysfunctions in synchronization of...
9.
Botti G, Bianchi A, Pavan B, Tedeschi P, Albanese V, Ferraro L, et al.
Int J Environ Res Public Health
. 2022 Sep;
19(17).
PMID: 36078325
Ferulic acid (Fer) is known for its antioxidant and anti-inflammatory activities, which are possibly useful against neurodegenerative diseases. Despite the ability of Fer to permeate the brain, its fast elimination...
10.
Valerii M, Turroni S, Ferreri C, Zaro M, Sansone A, Dalpiaz A, et al.
Pharmaceutics
. 2021 Nov;
13(11).
PMID: 34834168
Several studies showed that D-Limonene can improve metabolic parameters of obese mice via various mechanisms, including intestinal microbiota modulation. Nevertheless, its effective doses often overcome the acceptable daily intake, rising...