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Ghislaine Lacroix

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Articles 29
Citations 523
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Recent Articles
1.
Madiedo-Podvrsan S, Sebillet L, Martinez T, Bacari S, Zhu F, Cattelin M, et al.
Toxicol In Vitro . 2023 Jul; 92:105641. PMID: 37437822
Animal models are considered prime study models for inhalation-like toxicity assessment. However, in light of animal experimentation reduction (3Rs), we developed and investigated an alternative in vitro method to study...
2.
Bourgois A, Saurat D, De Araujo S, Boyard A, Guitard N, Renault S, et al.
Inhal Toxicol . 2021 Nov; 33(9-14):308-324. PMID: 34772293
Objective: Solid composite propellants combustion, in aerospace and defense fields, can lead to complex aerosols emission containing high concentrations of alumina nanoparticles (AlO NPs) and hydrogen chloride gas (HCl). Exposure...
3.
Lacroix G, Koch W, Ritter D, Gutleb A, Larsen S, Loret T, et al.
Appl In Vitro Toxicol . 2020 Sep; 4(2):91-106. PMID: 32953944
air-liquid interface (ALI) cell culture models can potentially be used to assess inhalation toxicology endpoints and are usually considered, in terms of relevancy, between classic (i.e., submerged) models and animal-based...
4.
Nelissen I, Haase A, Anguissola S, Rocks L, Jacobs A, Willems H, et al.
Nanomaterials (Basel) . 2020 Jul; 10(8). PMID: 32707981
The quality and relevance of nanosafety studies constitute major challenges to ensure their key role as a supporting tool in sustainable innovation, and subsequent competitive economic advantage. However, the number...
5.
Loret T, Rogerieux F, Trouiller B, Braun A, Egles C, Lacroix G
Part Fibre Toxicol . 2018 Jun; 15(1):25. PMID: 29866184
Background: Animal models remain at that time a reference tool to predict potential pulmonary adverse effects of nanomaterials in humans. However, in a context of reduction of the number of...
6.
Layachi S, Rogerieux F, Robidel F, Lacroix G, Bayat S
PLoS One . 2018 Jan; 8(5). PMID: 29364973
[This corrects the article DOI: 10.1371/journal.pone.0045687.].
7.
Dekali S, Gamez C, Kortulewski T, Blazy K, Rat P, Lacroix G
Toxicol Rep . 2017 Oct; 1:157-171. PMID: 28962236
As the lung is one of the main routes of exposure to manufactured nanoparticles, we developed an model resembling the alveolo-capillary barrier for the study of nanoparticle translocation. In order...
8.
Relier C, Dubreuil M, Lozano Garcia O, Cordelli E, Mejia J, Eleuteri P, et al.
Toxicol Sci . 2017 Jan; 156(2):527-537. PMID: 28087835
Inhaled titanium dioxide (TiO2) nanoparticles (NPs) can have negative health effects, and have been shown to cause respiratory tract cancer in rats. Inflammation has been linked to oxidative stress, and...
9.
Loret T, Peyret E, Dubreuil M, Aguerre-Chariol O, Bressot C, Le Bihan O, et al.
Part Fibre Toxicol . 2016 Dec; 13(1):58. PMID: 27919268
Background: Recently, much progress has been made to develop more physiologic in vitro models of the respiratory system and improve in vitro simulation of particle exposure through inhalation. Nevertheless, the...
10.
Hanot-Roy M, Tubeuf E, Guilbert A, Bado-Nilles A, Vigneron P, Trouiller B, et al.
Toxicol In Vitro . 2016 Mar; 33:125-35. PMID: 26928046
The health risks of nanoparticles remain a serious concern given their prevalence from industrial and domestic use. The primary route of titanium dioxide nanoparticle exposure is inhalation. The extent to...