Gerrald A Lodewijk
Overview
Explore the profile of Gerrald A Lodewijk including associated specialties, affiliations and a list of published articles.
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7
Citations
325
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Recent Articles
1.
Lodewijk G, de Geus M, Guimaraes R, Jacobs F
J Comp Neurol
. 2024 Jul;
532(7):e25648.
PMID: 38958676
In this study, we investigated recurrent copy number variations (CNVs) in the 19p12 locus, which are associated with neurodevelopmental disorders. The two genes in this locus, ZNF675 and ZNF681, arose...
2.
Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing
Lodewijk G, Kozuki S, Han C, Topacio B, Zargari A, Lee S, et al.
bioRxiv
. 2024 Mar;
PMID: 38496557
Embryonic stem cells (ESCs) can self-organize into developmental patterns with spatial organization and molecular similarity to that of early embryonic stages. This self-organization of ESCs requires transmission of signaling cues,...
3.
Zargari A, Lodewijk G, Mashhadi N, Cook N, Neudorf C, Araghbidikashani K, et al.
Cell Rep Methods
. 2023 Jul;
3(6):100500.
PMID: 37426758
Time-lapse microscopy is the only method that can directly capture the dynamics and heterogeneity of fundamental cellular processes at the single-cell level with high temporal resolution. Successful application of single-cell...
4.
Lodewijk G, Fernandes D, Vretzakis I, Savage J, Jacobs F
Mol Biol Evol
. 2020 Apr;
37(9):2531-2548.
PMID: 32330268
Ever since the availability of genomes from Neanderthals, Denisovans, and ancient humans, the field of evolutionary genomics has been searching for protein-coding variants that may hold clues to how our...
5.
Farmiloe G, Lodewijk G, Robben S, van Bree E, Jacobs F
Philos Trans R Soc Lond B Biol Sci
. 2020 Feb;
375(1795):20190333.
PMID: 32075554
The large family of KRAB zinc finger (KZNF) genes are transcription factors implicated in recognizing and repressing repetitive sequences such as transposable elements (TEs) in our genome. Through successive waves...
6.
Coulter M, Dorobantu C, Lodewijk G, Delalande F, Cianferani S, Ganesh V, et al.
Cell Rep
. 2018 Jul;
24(4):973-986.e8.
PMID: 30044992
Endosomal sorting complex required for transport (ESCRT) complex proteins regulate biogenesis and release of extracellular vesicles (EVs), which enable cell-to-cell communication in the nervous system essential for development and adult...
7.
Fiddes I, Lodewijk G, Mooring M, Bosworth C, Ewing A, Mantalas G, et al.
Cell
. 2018 Jun;
173(6):1356-1369.e22.
PMID: 29856954
Genetic changes causing brain size expansion in human evolution have remained elusive. Notch signaling is essential for radial glia stem cell proliferation and is a determinant of neuronal number in...