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Gerhard Unteregger

Explore the profile of Gerhard Unteregger including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 389
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Recent Articles
1.
Vitale G, Caraglia M, Jung V, Kamradt J, Gentilini D, Di Martino M, et al.
Cancers (Basel) . 2022 Jun; 14(12). PMID: 35740605
Background: Stromal components surrounding epithelial cancer cells seem to play a pivotal role during epithelial-to-mesenchymal transition (EMT), tumor invasion, and metastases. To identify the molecular mechanisms underlying tumor-stroma interactions may...
2.
de Mello Martins A, Allegretta G, Unteregger G, Haupenthal J, Eberhard J, Hoffmann M, et al.
J Steroid Biochem Mol Biol . 2017 Sep; 174:183-191. PMID: 28890368
CYP17A1-independent intratumoral steroid hormone synthesis is regarded as one possible explanation for resistance to treatment with the CYP17-inhibitor Abiraterone (Abi). The aim of our study was therefore to investigate the...
3.
Facchini G, Perri F, Misso G, DAniello C, Della Vittoria Scarpati G, Rossetti S, et al.
Curr Cancer Drug Targets . 2017 Feb; 18(5):457-467. PMID: 28183253
Prostate cancer is the most common malignancy in males and, despite a marked improvement in diagnostic techniques, a not small percentage of prostate tumours is still diagnosed in advanced stage....
4.
Saar M, Korbel C, Linxweiler J, Jung V, Kamradt J, Hasenfus A, et al.
Prostate . 2015 Jun; 75(14):1526-37. PMID: 26074274
Background: In vivo model systems in prostate cancer research that authentically reproduce tumor growth are still sparse. While orthotopic implantation is technically difficult, particularly in the mouse, most models favor...
5.
Korbel C, Jung V, Kamradt J, Stockle M, Unteregger G, Menger M, et al.
Urol Int . 2014 Aug; 94(3):347-53. PMID: 25115765
Introduction: Prostate cancer xenografts should prefer orthotopic growth to subcutaneous tumors as the former more closely mimics the natural tumor environment. However, these models are technically demanding and require an...
6.
Feola A, Cimini A, Migliucci F, Iorio R, Zuchegna C, Rothenberger R, et al.
J Cell Biochem . 2013 Apr; 114(9):2114-9. PMID: 23553770
Phosphoinositide 3-kinase proteins are composed by a catalytic p110 subunit and a regulatory p85 subunit. There are three classes of PI3K, named class I-III, on the bases of the protein...
7.
Greiner M, Kreutzer B, Lang S, Jung V, Cavalie A, Unteregger G, et al.
Prostate . 2011 May; 71(10):1074-83. PMID: 21557272
Background: We previously reported that over-expression of the SEC62 gene is a widespread phenomenon in prostate cancer. Since the use of endoplasmic reticulum (ER) stress-inducing substances such as thapsigargin in...
8.
Greiner M, Kreutzer B, Jung V, Grobholz R, Hasenfus A, Stohr R, et al.
Int J Cancer . 2010 Jul; 128(10):2284-95. PMID: 20669223
Sec62 is part of the protein translocation apparatus in the membrane of the endoplasmic reticulum (ER). In yeast, Sec62 participates in the post-translational translocation of proteins into the ER, but...
9.
Saar M, Korbel C, Jung V, Suttmann H, Grobholz R, Stockle M, et al.
Urol Oncol . 2010 May; 30(3):330-8. PMID: 20452251
Objectives: Orthotopic prostate cancer models are of great importance for cancer research. Orthotopic models in mice have been described previously. However, these studies lack a detailed methodological description and fail...
10.
Szczyrba J, Loprich E, Wach S, Jung V, Unteregger G, Barth S, et al.
Mol Cancer Res . 2010 Apr; 8(4):529-38. PMID: 20353999
Prostate cancer is a leading cause of tumor mortality. To characterize the underlying molecular mechanisms, we have compared the microRNA (miRNA) profile of primary prostate cancers and noncancer prostate tissues...