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Gerd Melkus

Explore the profile of Gerd Melkus including associated specialties, affiliations and a list of published articles. Areas
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Articles 60
Citations 527
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Recent Articles
1.
Brun-Vergara M, Melkus G, Chakraborty S, Zakhari N, Torres C, AlKherayf F, et al.
J Magn Reson Imaging . 2025 Feb; PMID: 39992022
Background: Edited MRS technique such as MEshcher-GArwood Point RESolved Spectroscopy (MEGA-PRESS) can determine isocitrate dehydrogenase mutation (IDH) mutation status in patients with gliomas but its accuracy in assessing glioma grade...
2.
Smith I, Sampaio M, Melkus G, Meier-Ross K, Chakraborty S, Stotts C, et al.
J Neuromuscul Dis . 2025 Feb; :22143602241304990. PMID: 39973404
Background: Oculopharyngeal muscular dystrophy (OPMD) is a rare, late-onset, slowly progressive neuromuscular disorder characterized by ptosis, dysphagia, and proximal limb weakness. Emerging clinical trials require rapidly accessible and sensitive biomarkers...
3.
Daniel E, Smith I, Sampaio M, Melkus G, Hamilton L, Bourque P, et al.
J Neuromuscul Dis . 2025 Feb; 11(6):1165-1179. PMID: 39967427
Inclusion body myositis (IBM) is an idiopathic muscle disorder primarily affecting adults above the age of 50. IBM is characterized by weakness in the knee extensor and deep finger flexor...
4.
Champagne A, Coverdale N, Skinner C, Schwarz B, Glikstein R, Melkus G, et al.
Brain Inj . 2024 Dec; :1-9. PMID: 39729051
Objective: The purpose of this study was to determine whether gray matter volume and diffusion-based metrics in associated white matter changed in breachers who had neuroimaging performed at two timepoints....
5.
Hamwi M, Thebault S, Melkus G, Auriat A, Pham A, Carrington A, et al.
Mult Scler Relat Disord . 2024 Nov; 80:105066. PMID: 39491411
Purpose: We sought to determine if structural network parameters add to traditional markers of MS treatment response following immunoablation and autologous haemopoietic stem cell transplantation (IAHSCT). The post-IAHSCT paradigm afforded...
6.
Glikstein R, Melkus G, De Oliveira E, Brun-Vergara M, Schwarz B, Ramsay T, et al.
J Magn Reson Imaging . 2024 May; 61(1):415-423. PMID: 38760963
Background: The Canadian Special Operations Forces Command conducts explosives operations and training which exposes members to explosive charges at close proximity. This 5-year longitudinal trial was conducted in follow-up to...
7.
Warman-Chardon J, Hartley T, Marshall A, McBride A, Couse M, MacDonald W, et al.
Neurol Genet . 2024 Jan; 9(5):e200088. PMID: 38235364
Background And Objectives: The human genome contains ∼20,000 genes, each of which has its own set of complex regulatory systems to govern precise expression in each developmental stage and cell...
8.
Sicard V, Fang Z, Kardish R, Healey K, Smith A, Reid S, et al.
J Neurotrauma . 2024 Jan; 41(5-6):552-570. PMID: 38204176
Emerging evidence suggests that advanced neuroimaging modalities such as arterial spin labelling (ASL) might have prognostic utility for pediatric concussion. This study aimed to: 1) examine group differences in global...
9.
Leduc-Pessah H, Smith I, Kernohan K, Sampaio M, Melkus G, Strasser L, et al.
J Neurol Sci . 2024 Jan; 457:122864. PMID: 38185014
Congenital myopathy with tremor (MYOTREM) is a recently described disorder characterized by mild myopathy and a postural and intention tremor present since early infancy. MYOTREM is associated with pathogenic variants...
10.
Trudel G, Melkus G, Liu T
Trends Endocrinol Metab . 2023 Dec; 35(2):85-87. PMID: 38040579
Knowledge is rapidly accumulating on basic roles and modulation of bone-marrow adipose tissue (BMAT). Among key modulators are physical forces on bones as exerted by gravity and exercise. Studying humans...