Gerard W Dougherty
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Explore the profile of Gerard W Dougherty including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1963
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Recent Articles
1.
Wohlgemuth K, Hoersting N, Koenig J, Loges N, Raidt J, George S, et al.
Eur Respir J
. 2024 Oct;
64(6).
PMID: 39362668
Background: Primary ciliary dyskinesia is a rare genetic disorder caused by insufficient mucociliary clearance leading to chronic airway infections. The diagnostic guideline of the European Respiratory Society primarily recommends an...
2.
Dougherty G, Ostrowski L, Nothe-Menchen T, Raidt J, Schramm A, Olbrich H, et al.
Am J Respir Crit Care Med
. 2024 Apr;
210(1):63-76.
PMID: 38626355
Bronchiectasis is a pathological dilatation of the bronchi in the respiratory airways associated with environmental or genetic causes (e.g., cystic fibrosis, primary ciliary dyskinesia, and primary immunodeficiency disorders), but most...
3.
Hjeij R, Aprea I, Poeta M, Nothe-Menchen T, Bracht D, Raidt J, et al.
Genet Med
. 2023 Feb;
25(5):100798.
PMID: 36727596
Purpose: Primary ciliary dyskinesia (PCD) is a heterogeneous disorder that includes respiratory symptoms, laterality defects, and infertility caused by dysfunction of motile cilia. Most PCD-causing variants result in abnormal outer...
4.
Biebach L, Cindric S, Koenig J, Aprea I, Dougherty G, Raidt J, et al.
Am J Respir Cell Mol Biol
. 2022 Sep;
67(3):409-413.
PMID: 36047773
No abstract available.
5.
Wallmeier J, Bracht D, Alsaif H, Dougherty G, Olbrich H, Cindric S, et al.
Am J Hum Genet
. 2021 Jun;
108(7):1318-1329.
PMID: 34077761
TP73 belongs to the TP53 family of transcription factors and has therefore been well studied in cancer research. Studies in mice, however, have revealed non-oncogenic activities related to multiciliogenesis. Utilizing...
6.
Aprea I, Nothe-Menchen T, Dougherty G, Raidt J, Loges N, Kaiser T, et al.
Mol Hum Reprod
. 2021 Feb;
27(3).
PMID: 33561200
Motile cilia line the efferent ducts of the mammalian male reproductive tract. Several recent mouse studies have demonstrated that a reduced generation of multiple motile cilia in efferent ducts is...
7.
Dougherty G, Mizuno K, Nothe-Menchen T, Ikawa Y, Boldt K, Ta-Shma A, et al.
Nat Commun
. 2020 Nov;
11(1):5520.
PMID: 33139725
Axonemal dynein ATPases direct ciliary and flagellar beating via adenosine triphosphate (ATP) hydrolysis. The modulatory effect of adenosine monophosphate (AMP) and adenosine diphosphate (ADP) on flagellar beating is not fully...
8.
Alfieri M, Iaconis D, Tammaro R, Perone L, Cali G, Nitsch L, et al.
Tissue Cell
. 2020 Jun;
64:101369.
PMID: 32473706
Oral-Facial-Digital type I (OFD1) is a rare inherited form of renal cystic disease associated with ciliary dysfunction. This disorder is due to mutations in the OFD1 gene that encodes a...
9.
Chivukula R, Montoro D, Leung H, Yang J, Shamseldin H, Taylor M, et al.
Nat Med
. 2020 Jan;
26(2):300.
PMID: 31996837
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Chivukula R, Montoro D, Leung H, Yang J, Shamseldin H, Taylor M, et al.
Nat Med
. 2020 Jan;
26(2):244-251.
PMID: 31959991
Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types,...