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Gerald W Valentine

Explore the profile of Gerald W Valentine including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 578
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Recent Articles
1.
Valentine G, DeVito E, Jatlow P, Gueorguieva R, Sofuoglu M
J Psychopharmacol . 2018 May; 32(9):986-994. PMID: 29788802
Objective: This double-blind, placebo controlled study examined whether menthol inhaled from an electronic cigarette (e-cigarette) would change subjective and withdrawal alleviating effects of intravenous nicotine in young adult smokers. Methods:...
2.
Valentine G, Hefner K, Jatlow P, Rosenheck R, Gueorguieva R, Sofuoglu M
J Dual Diagn . 2017 Oct; 14(1):2-13. PMID: 29083287
Objective: Compared to the general U.S. population, smokers with comorbid psychiatric and/or substance use disorders have lower quit rates after evidence-based treatments and disproportionately high smoking-related deaths. Improved modalities for...
3.
DeVito E, Valentine G, Herman A, Jensen K, Sofuoglu M
Tob Regul Sci . 2017 Sep; 2(4):317-328. PMID: 28890914
Objectives: Menthol, a flavoring agent, is found in approximately 90% of cigarettes, but at much higher levels in menthol than non-menthol cigarettes. Menthol is reportedly included in cigarettes for its...
4.
MacLean R, Valentine G, Jatlow P, Sofuoglu M
Alcohol Clin Exp Res . 2017 Jan; 41(2):238-250. PMID: 28054395
Decades of alcohol research have established the health risks and pharmacodynamic profile of oral alcohol consumption. Despite isolated periods of public health concern, comparatively less research has evaluated exposure to...
5.
Valentine G, Jatlow P, Coffman M, Nadim H, Gueorguieva R, Sofuoglu M
Drug Alcohol Depend . 2016 Jan; 159:272-6. PMID: 26778759
Background: The liquids (e-liquids) used in an electronic cigarette (e-cigarette) contain myriad chemicals without adequate human inhalation safety data. Furthermore, the absence of e-liquid labeling requirements poses a formidable challenge...
6.
Jensen K, DeVito E, Herman A, Valentine G, Gelernter J, Sofuoglu M
Neuropsychopharmacology . 2015 May; 40(12):2813-21. PMID: 25948103
Genome-wide association studies have implicated the CHRNA5-CHRNA3-CHRNB4 gene cluster in risk for heavy smoking and several smoking-related disorders. The heavy smoking risk allele might reduce the aversive effects of nicotine,...
7.
DeVito E, Herman A, Waters A, Valentine G, Sofuoglu M
Neuropsychopharmacology . 2013 Dec; 39(6):1431-40. PMID: 24345818
Nicotine dependence is a serious public health concern. Optimal treatment of nicotine dependence will require greater understanding of the mechanisms that contribute to the maintenance of smoking behaviors. A growing...
8.
Morgan P, Pace-Schott E, Mason G, Forselius E, Fasula M, Valentine G, et al.
Sleep . 2012 Jun; 35(6):807-14. PMID: 22654200
Study Objectives: GABA is increasingly recognized as an important neurotransmitter for the initiation and maintenance of sleep. We sought to measure cortical GABA content through proton magnetic resonance spectroscopy (MRS)...
9.
Valentine G, Mason G, Gomez R, Fasula M, Watzl J, Pittman B, et al.
Psychiatry Res . 2011 Jan; 191(2):122-7. PMID: 21232924
The NMDA receptor antagonist ketamine can induce a rapid improvement in depressive symptoms that often endures for days after a single intravenous dose. The pharmacodynamic basis for this effect is...
10.
Valentine G, Sanacora G
Biochem Pharmacol . 2009 Apr; 78(5):431-9. PMID: 19376090
Accumulating evidence indicates that dysfunction in amino acid neurotransmission contributes to the pathophysiology of depression. Consequently, the modulation of amino acid neurotransmission represents a new strategy for antidepressant development. While...