Gerald H Thomsen
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Explore the profile of Gerald H Thomsen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Bossert P, Thomsen G
J Vis Exp
. 2017 Jan;
(119).
PMID: 28117771
Cnidarians, and specifically Hydra, were the first animals shown to regenerate damaged or severed structures, and indeed such studies arguably launched modern biological inquiry through the work of Trembley more...
2.
Gillis W, Kirmizitas A, Iwasaki Y, Ki D, Wyrick J, Thomsen G
Cell Commun Signal
. 2016 Aug;
14(1):15.
PMID: 27484226
Background: Canonical Wnt signals, transduced by stabilized β-catenin, play similar roles across animals in maintaining stem cell pluripotency, regulating cell differentiation, and instructing normal embryonic development. Dysregulated Wnt/β-catenin signaling causes...
3.
Iwasaki Y, Thomsen G
Development
. 2014 Sep;
141(19):3740-51.
PMID: 25209246
Alternative splicing of pre-mRNAs is an important means of regulating developmental processes, yet the molecular mechanisms governing alternative splicing in embryonic contexts are just beginning to emerge. Polyglutamine-binding protein 1...
4.
Kirmizitas A, Gillis W, Zhu H, Thomsen G
Dev Biol
. 2014 May;
392(2):358-67.
PMID: 24858484
Smad proteins convey canonical intracellular signals for activated receptors in the TGFβ superfamily, but the activity of Smads and their impact on target genes are further regulated by a wide...
5.
Nakayama T, Fish M, Fisher M, Oomen-Hajagos J, Thomsen G, Grainger R
Genesis
. 2013 Oct;
51(12):835-43.
PMID: 24123613
We have assessed the efficacy of the recently developed CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system for genome modification in the amphibian Xenopus tropicalis. As a model experiment, targeted...
6.
Bossert P, Dunn M, Thomsen G
Dev Dyn
. 2013 Aug;
242(11):1320-31.
PMID: 23913838
Background: As the sea anemone Nematostella vectensis emerges as a model for studying regeneration, new tools will be needed to assess its regenerative processes and describe perturbations resulting from experimental...
7.
Sorrentino G, Gillis W, Oomen-Hajagos J, Thomsen G
Evodevo
. 2012 Oct;
3(1):22.
PMID: 23020873
Unlabelled: Background: Activity of the Transforming growth factor-β (TGFβ) pathway is essential to the establishment of body axes and tissue differentiation in bilaterians. Orthologs for core pathway members have been...
8.
Callery E, Park C, Xu X, Zhu H, Smith J, Thomsen G
Open Biol
. 2012 Jun;
2(4):120060.
PMID: 22724065
Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs) act via Smads 1, 5 and 8 and TGF-βs signal through Smads 2 and 3....
9.
Gersch R, Kirmizitas A, Sobkow L, Sorrentino G, Thomsen G, Hadjiargyrou M
Gene Expr Patterns
. 2012 Jan;
12(3-4):145-53.
PMID: 22281807
Mustn1 is a vertebrate-specific protein that, in vitro, was showed to be essential for prechondrocyte function and thus it has the potential to regulate chondrogenesis during embryonic development. We use...
10.
Callery E, Thomsen G, Smith J
Dev Biol
. 2010 Jan;
340(1):75-87.
PMID: 20083100
T-box family transcription factors play many roles in Metazoan development. Here we characterise Tbx6r, a unique Tbx6 paralogue isolated from the amphibian Xenopus. The evolution and developmental integration of this...