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Georgia Valsami

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Articles 83
Citations 534
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Recent Articles
1.
Zoupanou N, Papakyriakopoulou P, Georgiou N, Cheilari A, Javornik U, Podbevsek P, et al.
Molecules . 2025 Mar; 30(5). PMID: 40076392
Donepezil (DH), a selective acetylcholinesterase inhibitor, is widely used to manage symptoms of mild to moderate Alzheimer's disease by enhancing cholinergic neurotransmission and preventing acetylcholine breakdown. Despite the effectiveness of...
2.
Katsaros I, Sotiropoulou M, Vailas M, Papachristou F, Papakyriakopoulou P, Grigoriou M, et al.
Nutrients . 2025 Jan; 16(24. PMID: 39770904
Non-alcoholic fatty liver disease (NAFLD) is a major metabolic disorder with no established pharmacotherapy. Quercetin, a polyphenolic flavonoid, demonstrates potential hepatoprotective effects but has limited bioavailability. This study evaluates the...
3.
Katsaros I, Sotiropoulou M, Vailas M, Kapetanakis E, Valsami G, Tsaroucha A, et al.
Nutrients . 2024 Nov; 16(22). PMID: 39599578
Metabolic dysfunction-associated fatty liver disease (MASLD) is a widespread liver disorder characterized by excessive fat accumulation in the liver, commonly associated with metabolic syndrome components such as obesity, diabetes, and...
4.
Papakyriakopoulou P, Balafas E, Kostomitsopoulos N, Rekkas D, Dev K, Valsami G
Pharm Res . 2024 Oct; 41(10):1951-1963. PMID: 39470941
Background: Fingolimod hydrochloride (FH) has emerged as a vital medication for managing Multiple Sclerosis (MS). Despite its high oral bioavailability of 93%, it is plagued by slow oral absorption (T ...
5.
Triantafyllopoulou E, Perinelli D, Forys A, Pantelis P, Gorgoulis V, Lagopati N, et al.
Pharmaceutics . 2024 Sep; 16(9). PMID: 39339240
Despite the appealing properties of random copolymers, the use of these biomaterials in association with phospholipids is still limited, as several aspects of their performance have not been investigated. The...
6.
Kadoglou N, Stasinopoulou M, Velidakis N, Khattab E, Christodoulou E, Gkougkoudi E, et al.
Rev Cardiovasc Med . 2024 Jul; 25(2):51. PMID: 39077343
Vascular calcification (VC) is a complex process of calcium deposition on the arterial wall and atherosclerotic plaques and involves interaction between vascular smooth muscle cells, inflammatory and VC mediators. The...
7.
Saitani E, Pippa N, Perinelli D, Forys A, Papakyriakopoulou P, Lagopati N, et al.
J Mater Chem B . 2024 May; 12(27):6587-6604. PMID: 38804576
In this study, we designed and developed systems composed of poly(ethylene-oxide)--poly(ε-caprolactone) block copolymers of different molecular weights and compositions, non-ionic surfactant, and cyclodextrins. The innovation of this study lies in...
8.
Triantafyllopoulou E, Forys A, Perinelli D, Balafouti A, Karayianni M, Trzebicka B, et al.
Langmuir . 2024 May; 40(23):11936-11946. PMID: 38797979
Lipid/copolymer colloidal systems are deemed hybrid materials with unique properties and functionalities. Their hybrid nature leads to complex interfacial phenomena, which have not been fully encoded yet, navigating their properties....
9.
Papakyriakopoulou P, Valsami G, Dev K
Mol Neurobiol . 2024 Apr; 61(11):8688-8701. PMID: 38558359
Krabbe disease (KD) is a rare demyelinating disorder characterized by demyelination caused by mutations in the GALC gene, resulting in toxic accumulation of psychosine. Psychosine has been identified as detrimental...
10.
Saitani E, Pippa N, Perinelli D, Forys A, Papakyriakopoulou P, Lagopati N, et al.
Int J Mol Sci . 2024 Jan; 25(2). PMID: 38256239
Ropinirole is a non-ergolinic dopamine agonist used to manage Parkinson's disease and it is characterized by poor oral bioavailability. This study aimed to design and develop advanced drug delivery systems...