George W Liechti
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Explore the profile of George W Liechti including associated specialties, affiliations and a list of published articles.
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17
Citations
136
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Recent Articles
1.
Broder K, Matrosova V, Tkavc R, Gaidamakova E, Ho L, Macintyre A, et al.
NPJ Vaccines
. 2024 Nov;
9(1):207.
PMID: 39528548
Chlamydia trachomatis infections are the most common bacterial STIs globally and can lead to serious morbidity if untreated. Development of a killed, whole-cell vaccine has been stymied by coincident epitope...
2.
Diallo A, Overman G, Sah P, Liechti G
Infect Immun
. 2024 Jun;
92(7):e0006324.
PMID: 38899879
Toll-like receptor 9 (TLR9) is an innate immune receptor that localizes to endosomes in antigen presenting cells and recognizes single stranded unmethylated CpG sites on bacterial genomic DNA (gDNA). Previous...
3.
Druffner S, Venkateshwaraprabu S, Khadka S, Duncan B, Morris M, Sen-Kilic E, et al.
Microbiol Spectr
. 2024 Apr;
12(6):e0001524.
PMID: 38682907
Importance: Mouse infection models with species are widely used to study pathogenesis and gastric cancer initiation. However, is not a natural mouse pathogen, and mouse-adapted strains are poorly immunogenic. In...
4.
Diallo A, Overman G, Sah P, Liechti G
bioRxiv
. 2024 Feb;
PMID: 38370826
Toll-like receptor 9 (TLR9) is an innate immune receptor that localizes to endosomes in antigen presenting cells and recognizes single stranded unmethylated CpG sites on bacterial genomic DNA. Previous bioinformatic...
5.
Druffner S, Venkateshwaraprabu S, Khadka S, Duncan B, Morris M, Sen-Kilic E, et al.
bioRxiv
. 2024 Jan;
PMID: 38187587
Background: Gastric cancer is the fifth most diagnosed cancer in the world. Infection by the bacteria (HP) is associated with approximately 75% of gastric cancer cases. HP infection induces chronic...
6.
Ball L, Bronstein E, Liechti G, Maurelli A
Infect Immun
. 2023 Nov;
92(1):e0017923.
PMID: 38014981
and are the most prevalent bacterial sexually transmitted infections (STIs) globally. Despite frequent co-infections in patients, few studies have investigated how mono-infections may differ from co-infections. We hypothesized that a...
7.
Liechti G
Front Microbiol
. 2021 Dec;
12:733850.
PMID: 34956109
Cell size regulation in bacteria is a function of two basic cellular processes: the expansion of the cell envelope and its constriction at spatially defined points at what will eventually...
8.
Brockett M, Liechti G
Infect Immun
. 2021 May;
89(8):e0068520.
PMID: 34001559
In response to stress, the obligate intracellular pathogen Chlamydia trachomatis stops dividing and halts its biphasic developmental cycle. The infectious, extracellular form of this bacterium is highly susceptible to killing...
9.
Brockett M, Lee J, Cox J, Liechti G, Ouellette S
Infect Immun
. 2021 May;
89(8):e0020321.
PMID: 33941579
Bactofilins are polymer-forming cytoskeletal proteins that are widely conserved in bacteria. Members of this protein family have diverse functional roles such as orienting subcellular molecular processes, establishing cell polarity, and...
10.
Brothwell J, Brockett M, Banerjee A, Stein B, Nelson D, Liechti G
J Bacteriol
. 2021 Jan;
203(6).
PMID: 33431433
DNA replication is essential for the growth and development of , however it is unclear how this process contributes to and is controlled by the pathogen's biphasic lifecycle. While inhibitors...