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George Niotis

Explore the profile of George Niotis including associated specialties, affiliations and a list of published articles. Areas
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Citations 33
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Recent Articles
1.
Arvanitaki E, Goulielmaki E, Gkirtzimanaki K, Niotis G, Tsakani E, Nenedaki E, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(17):e2317402121. PMID: 38635632
DNA damage and neurodegenerative disorders are intimately linked but the underlying mechanism remains elusive. Here, we show that persistent DNA lesions in tissue-resident macrophages carrying an XPF-ERCC1 DNA repair defect...
2.
Chatzidoukaki O, Stratigi K, Goulielmaki E, Niotis G, Akalestou-Clocher A, Gkirtzimanaki K, et al.
Sci Adv . 2021 Nov; 7(47):eabj5769. PMID: 34797720
How DNA damage leads to chronic inflammation and tissue degeneration with aging remains to be fully resolved. Here, we show that DNA damage leads to cellular senescence, fibrosis, loss-of-tissue architecture,...
3.
Siametis A, Niotis G, Garinis G
J Invest Dermatol . 2021 Jan; 141(4S):961-967. PMID: 33494932
In mammals, genome instability and aging are intimately linked as illustrated by the growing list of patients with progeroid and animal models with inborn DNA repair defects. Until recently, DNA...