George C Mayne
Overview
Explore the profile of George C Mayne including associated specialties, affiliations and a list of published articles.
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31
Citations
336
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0
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Recent Articles
1.
Mayne G, Woodman R, Watson D, Bright T, Gan S, Lord R, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108236
The biomarker development field within molecular medicine remains limited by the methods that are available for building predictive models. We developed an efficient method for estimating confidence intervals for the...
2.
Eichelmann A, Mayne G, Chiam K, Due S, Bastian I, Butz F, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34074015
gene mutations occur in 70% of oesophageal adenocarcinomas (OACs). Given the central role of p53 in controlling cellular response to therapy we investigated the role of mutant (mut-) p53 and...
3.
Butz F, Eichelmann A, Mayne G, Wang T, Bastian I, Chiam K, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33255413
Many patients with Oesophageal Adenocarcinoma (OAC) do not benefit from chemoradiotherapy treatment due to therapy resistance. To better understand the mechanisms involved in resistance and to find potential biomarkers, we...
4.
Chiam K, Mayne G, Wang T, Watson D, Irvine T, Bright T, et al.
World J Gastroenterol
. 2020 Jun;
26(20):2570-2583.
PMID: 32523312
Background: Circulating microRNAs (miRNAs) are potential biomarkers for many diseases. However, they can originate from non-disease specific sources, such as blood cells, and compromise the investigations for miRNA biomarkers. While...
5.
Mayne G, Watson D, Chiam K, Hussey D
Ann Surg Oncol
. 2018 Oct;
25(Suppl 3):755-756.
PMID: 30362067
No abstract available.
6.
Chiam K, Mayne G, Watson D, Woodman R, Bright T, Michael M, et al.
Ann Surg Oncol
. 2018 Jul;
25(9):2731-2738.
PMID: 29987600
Background: Clinical trials report improved overall survival following neoadjuvant chemoradiotherapy in patients undergoing surgery for esophageal adenocarcinoma, with a 10-15% survival improvement. MicroRNAs (miRNAs) are small noncoding RNAs that are...
7.
Sreedharan L, Mayne G, Watson D, Bright T, Lord R, Ansar A, et al.
World J Gastroenterol
. 2017 Aug;
23(30):5508-5518.
PMID: 28852310
Aim: To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. Methods: High throughput screening using TaqMan Array Human MicroRNA quantitative...
8.
Lindblad M, Bright T, Schloithe A, Mayne G, Chen G, Bull J, et al.
World J Surg
. 2016 Nov;
41(4):1023-1034.
PMID: 27882416
Background: Endoscopic surveillance of Barrett's esophagus (BE) is probably not cost-effective. A sub-population with BE at increased risk of high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) who could be targeted...
9.
Koetje J, Nieuwenhuijs V, Irvine T, Mayne G, Watson D
World J Surg
. 2016 Jan;
40(5):1137-44.
PMID: 26757716
Introduction: Outcome following fundoplication for gastroesophageal reflux can be measured using objective tests, symptom scores and quality of life (QoL) measures. Which is best and how these assessments correlate is...
10.
Chiam K, Wang T, Watson D, Mayne G, Irvine T, Bright T, et al.
J Gastrointest Surg
. 2015 May;
19(7):1208-15.
PMID: 25943911
Background: The poor prognosis and rising incidence of esophageal adenocarcinoma highlight the need for improved detection methods. The potential for circulating microRNAs (miRNAs) as biomarkers in other cancers has been...