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Georg Spinka

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Articles 43
Citations 194
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Recent Articles
1.
Dannenberg V, Zschocke F, Halavina K, Mascherbauer K, Heitzinger G, Koschutnik M, et al.
Eur J Clin Invest . 2024 Dec; 55(3):e14367. PMID: 39623565
Background: Severe tricuspid regurgitation (TR) is associated with high morbidity and mortality. Isolated TR, defined as TR without overt heart disease, is typical and offers limited cardiac treatment options other...
2.
Halavina K, Koschutnik M, Dona C, Autherith M, Petric F, Rockel A, et al.
JACC Cardiovasc Interv . 2024 Sep; 17(17):2054-2066. PMID: 39260962
Background: Fluid overload (FO) subjects patients with severe aortic stenosis (AS) to increased risk for heart failure and death after valve replacement and can be objectively quantified using bioimpedance spectroscopy...
3.
Heitzinger G, Spinka G, Prausmuller S, Pavo N, Dannenberg V, Dona C, et al.
JACC Adv . 2024 Jun; 1(3):100063. PMID: 38938405
Background: Secondary mitral regurgitation (sMR) in the setting of heart failure (HF) has considerable impact on quality of life, HF rehospitalizations, and mortality. Identification of high-risk cohorts is essential to...
4.
Wurm R, Prausmuller S, Ponleitner M, Spinka G, Weidenhammer A, Arfsten H, et al.
JACC Heart Fail . 2024 Jun; 12(6):1073-1085. PMID: 38839151
Background: Cognitive impairment is prevalent in patients with heart failure with reduced ejection fraction (HFrEF), affecting self-care and outcomes. Novel blood-based biomarkers have emerged as potential diagnostic tools for neurodegeneration....
5.
Arfsten H, Heitzinger G, Prausmuller S, Weidenhammer A, Goliasch G, Bartko P, et al.
ESC Heart Fail . 2024 Mar; 11(3):1748-1757. PMID: 38459668
Aims: Regulation of the renin-angiotensin system (RAS) in heart failure (HF) with reduced ejection fraction (HFrEF) still raises questions, as a large proportion of patients show normal renin levels despite...
6.
Demirel C, Winter M, Nitsche C, Koschatko S, Jantsch C, Mascherbauer K, et al.
Eur Heart J Cardiovasc Imaging . 2024 Jan; 25(5):718-726. PMID: 38236149
Aims: Transcatheter aortic valve replacement (TAVR) revolutionized the therapy of severe aortic stenosis (AS) with rising numbers. Mixed aortic valve disease (MAVD) treated by TAVR is gaining more interest, as...
7.
Weidenhammer A, Prausmuller S, Partsch C, Spinka G, Luckerbauer B, Larch M, et al.
Cells . 2023 Dec; 12(24). PMID: 38132152
Background: CILP-1 regulates myocardial fibrotic response and remodeling and was reported to indicate right ventricular dysfunction (RVD) in pulmonary hypertension (PH) and heart failure (HF). This study examines CILP-1 as...
8.
Han E, Prausmuller S, Weidenhammer A, Spinka G, Arfsten H, Bartko P, et al.
J Renin Angiotensin Aldosterone Syst . 2023 Nov; 2023:8883145. PMID: 37941680
Introduction: The renin-angiotensin system (RAS) is the main target of neurohumoral therapy in heart failure with reduced ejection fraction (HFrEF) effectively reducing mortality. Reasonably, renin might serve as a biomarker...
9.
Koschutnik M, Dona C, Nitsche C, Kammerlander A, Dannenberg V, Brunner C, et al.
Clin Res Cardiol . 2023 Oct; 114(2):156-167. PMID: 37870628
Background: Right ventricular-to-pulmonary artery (RV-PA) coupling has recently been shown to be associated with outcome in valvular heart disease. However, longitudinal data on RV dysfunction and reverse cardiac remodeling in...
10.
Prausmuller S, Weidenhammer A, Heitzinger G, Spinka G, Goliasch G, Arfsten H, et al.
Eur J Prev Cardiol . 2023 May; 30(12):1247-1254. PMID: 37210596
Aims: Heart failure with preserved ejection fraction (HFpEF) is a condition that commonly coexists with type 2 diabetes mellitus (T2DM) and obesity. Whether the obesity-related survival benefit generally observed in...