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Geoffrey Topping

Explore the profile of Geoffrey Topping including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 218
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Recent Articles
1.
Bliemsrieder E, Kaissis G, Grashei M, Topping G, Altomonte J, Hundshammer C, et al.
Sci Rep . 2021 May; 11(1):11705. PMID: 34050211
No abstract available.
2.
Bliemsrieder E, Kaissis G, Grashei M, Topping G, Altomonte J, Hundshammer C, et al.
Sci Rep . 2021 Jan; 11(1):1191. PMID: 33441943
The in vivo assessment of tissue metabolism represents a novel strategy for the evaluation of oncologic disease. Hepatocellular carcinoma (HCC) is a high-prevalence, high-mortality tumor entity often discovered at a...
3.
Dantes Z, Yen H, Pfarr N, Winter C, Steiger K, Muckenhuber A, et al.
JCI Insight . 2020 Jul; 5(15). PMID: 32614802
One of the major challenges in using pancreatic cancer patient-derived organoids (PDOs) in precision oncology is the time from biopsy to functional characterization. This is particularly true for endoscopic ultrasound-guided...
4.
Varasteh Z, Mohanta S, Robu S, Braeuer M, Li Y, Omidvari N, et al.
J Nucl Med . 2019 Aug; 60(12):1743-1749. PMID: 31405922
Heart failure remains a major source of late morbidity and mortality after myocardial infarction (MI). The temporospatial presence of activated fibroblasts in the injured myocardium predicts the quality of cardiac...
5.
Abdullahi S, Jakel M, Behrend S, Steiger K, Topping G, Krabbe T, et al.
J Virol . 2018 Sep; 92(23). PMID: 30232179
Oncolytic viruses represent an exciting new aspect of the evolving field of cancer immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis virus (VSV) and Newcastle disease virus...
6.
Omidvari N, Topping G, Cabello J, Paul S, Schwaiger M, Ziegler S
Phys Med Biol . 2018 Mar; 63(9):095002. PMID: 29582780
Compromises in the design of a positron emission tomography (PET) insert for a magnetic resonance imaging (MRI) system should minimize the deterioration of image quality in both modalities, particularly when...
7.
Hundshammer C, Duwel S, Ruseckas D, Topping G, Dzien P, Muller C, et al.
Sensors (Basel) . 2018 Feb; 18(2). PMID: 29462891
pH is a tightly regulated physiological parameter that is often altered in diseased states like cancer. The development of biosensors that can be used to non-invasively image pH with hyperpolarized...
8.
Omidvari N, Cabello J, Topping G, Schneider F, Paul S, Schwaiger M, et al.
Phys Med Biol . 2017 Oct; 62(22):8671-8692. PMID: 28976912
MADPET4 is the first small animal PET insert with two layers of individually read out crystals in combination with silicon photomultiplier technology. It has a novel detector arrangement, in which...
9.
Kubala E, Munoz-Alvarez K, Topping G, Hundshammer C, Feuerecker B, Gomez P, et al.
J Vis Exp . 2017 Jan; (118). PMID: 28060330
In the past decades, new methods for tumor staging, restaging, treatment response monitoring, and recurrence detection of a variety of cancers have emerged in conjunction with the state-of-the-art positron emission...