Geoffrey E Hespe
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Explore the profile of Geoffrey E Hespe including associated specialties, affiliations and a list of published articles.
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33
Citations
528
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Recent Articles
11.
Nunez J, Strong A, Comish P, Hespe G, Harvey J, Sorkin M, et al.
Adv Wound Care (New Rochelle)
. 2022 Aug;
12(2):68-84.
PMID: 35951024
Laser use has become part of the gold standard of treatment as an effective adjuvant in multimodal therapy for pathologic scarring caused by burns, trauma, acne, and surgery, as well...
12.
Hespe G, Stepien D, Sherif R, Gilman R
Aesthet Surg J Open Forum
. 2021 Aug;
3(3):ojab025.
PMID: 34423294
Umbilicoplasty is a key component of any abdominoplasty as the umbilicus has been described as the central aesthetic subunit to the abdomen. Here, we describe our preferred technique for umbilicoplasty...
13.
Edwards N, Hobson E, Dey D, Rhodes A, Overmann A, Hoyt B, et al.
Stem Cells Dev
. 2021 Mar;
30(9):473-484.
PMID: 33715398
Heterotopic ossification (HO) is a devastating condition in which ectopic bone forms inappropriately in soft tissues following traumatic injuries and orthopedic surgeries as a result of aberrant mesenchymal progenitor cell...
14.
Pagani C, Huber A, Hwang C, Marini S, Padmanabhan K, Livingston N, et al.
Stem Cell Reports
. 2021 Feb;
16(3):626-640.
PMID: 33606989
Heterotopic ossification (HO) is a form of pathological cell-fate change of mesenchymal stem/precursor cells (MSCs) that occurs following traumatic injury, limiting range of motion in extremities and causing pain. MSCs...
15.
Edwards N, Hwang C, Marini S, Pagani C, Spreadborough P, Rowe C, et al.
FASEB J
. 2020 Oct;
34(12):15753-15770.
PMID: 33089917
Ischemia reperfusion (IR) injury results in devastating skeletal muscle fibrosis. Here, we recapitulate this injury with a mouse model of hindlimb IR injury which leads to skeletal muscle fibrosis. Injury...
16.
Kokosis G, Vorstenbosch J, Lombardi A, Shamsunder M, Mehrara B, Hespe G, et al.
Plast Reconstr Surg Glob Open
. 2020 Sep;
8(8):e2988.
PMID: 32983763
Chronic complications following anterior cranial fossa tumor extirpation, such as cerebrospinal fluid leak, meningitis, mucocele, pneumocephalus, and abscess, negatively impact patient quality of life. Robust vascularized tissue is generally required...
17.
Rehal S, Kataru R, Hespe G, Baik J, Park H, Ly C, et al.
Mol Metab
. 2020 Sep;
42:101081.
PMID: 32941994
Objective: Obesity results in lymphatic dysfunction, but the cellular mechanisms that mediate this effect remain largely unknown. Previous studies in obese mice have shown that inducible nitric oxide synthase-expressing (iNOS)...
18.
Bennett K, Hespe G, Vercler C, Buchman S
J Craniofac Surg
. 2019 Jan;
30(2):458-464.
PMID: 30640851
Background: Minimally invasive approaches for the treatment of single-suture craniosynostosis are sometimes touted as equivalent to cranial vault reconstruction. While techniques for sagittal synostosis have been reviewed previously, evidence regarding...
19.
Hespe G, Ly C, Kataru R, Mehrara B
Plast Reconstr Surg
. 2018 Dec;
143(1):77e-87e.
PMID: 30589786
Background: Genetic mutations and obesity increase the risk of secondary lymphedema, suggesting that impaired lymphatic function before surgical injury may contribute to disease pathophysiology. Previous studies show that obesity not...
20.
Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al.
Nat Commun
. 2018 May;
9(1):1970.
PMID: 29773802
T cell-mediated responses have been implicated in the development of fibrosis, impaired lymphangiogenesis, and lymphatic dysfunction in secondary lymphedema. Here we show that CD4 T cells are necessary for lymphedema ...