Geoff Pavey
Overview
Explore the profile of Geoff Pavey including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
120
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Recent Articles
1.
Sekiguchi H, Pavey G, Dean B
J Affect Disord
. 2022 Sep;
320:313-318.
PMID: 36162690
Dopamine dysregulation is known to play a major role in the pathophysiology of major depressive disorders (MDD) and bipolar disorders (BD). The dopamine transporter (DAT) plays a critical role in...
2.
Sekiguchi H, Pavey G, Dean B
NPJ Schizophr
. 2019 Dec;
5(1):20.
PMID: 31792225
The dopamine hypothesis proposes that there is a hypodopaminergic state in the prefrontal cortex and a hyperdopaminergic state in the striatum of patients with schizophrenia. Evidence suggests the hyperdopaminergic state...
3.
McOmish C, Pavey G, McLean C, Horne M, Dean B, Scarr E
J Neural Transm (Vienna)
. 2016 Nov;
124(2):227-236.
PMID: 27873015
Parkinson's disease (PD) is a devastating disorder, affecting approximately 2% of people aged 60 and above. It is marked by progressive neurodegeneration that has long been known to impact dopaminergic...
4.
McOmish C, Pavey G, Gibbons A, Hopper S, Udawela M, Scarr E, et al.
J Affect Disord
. 2015 Nov;
190:241-248.
PMID: 26521087
Introduction: The glutamatergic system has recently been implicated in the pathogenesis and treatment of major depressive disorders(MDD) and mGlu2/3 receptors play an important role in regulating glutamatergic tone. We therefore...
5.
Chavez C, Hollaus M, Scarr E, Pavey G, Gogos A, van den Buuse M
Brain Res
. 2010 Jan;
1321:51-9.
PMID: 20079719
The aim of the present study was to elucidate the effect of estrogen on dopaminergic and serotonergic regulation of prepulse inhibition (PPI) by measuring its effects on the density of...
6.
Matsumoto I, Inoue Y, Iwazaki T, Pavey G, Dean B
Neurosci Lett
. 2005 Apr;
379(3):164-8.
PMID: 15843056
Although evidence suggests that 5-HT(2A) and muscarinic M1/M4 receptors are implicated in the pathology of schizophrenia, the results are not conclusive. In the present study we tested the hypothesis that...
7.
Smith M, Sharples R, Evin G, McLean C, Dean B, Pavey G, et al.
Brain Res Mol Brain Res
. 2004 Aug;
127(1-2):128-35.
PMID: 15306129
We have analysed the expression of a truncated variant presenilin 2 protein (PS2V) in frontal cortex from subjects with Alzheimer's disease (AD) and age-matched controls, and compared these results with...