Genevieve Hartley
Overview
Explore the profile of Genevieve Hartley including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
110
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0
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Recent Articles
1.
Najem H, Lea S, Tripathi S, Hurley L, Chen C, William I, et al.
J Clin Invest
. 2024 Jun;
134(12).
PMID: 38941297
STING agonists can reprogram the tumor microenvironment to induce immunological clearance within the central nervous system. Using multiplexed sequential immunofluorescence (SeqIF) and the Ivy Glioblastoma Atlas, STING expression was found...
2.
Hsieh R, Krishnan S, Wu R, Boda A, Liu A, Winkler M, et al.
Sci Immunol
. 2022 Jun;
7(72):eabl9330.
PMID: 35687697
Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically. However, abscopal tumor remissions are extremely rare, and the postirradiation immune escape mechanisms...
3.
Hartley G, Elmslie R, Murphy B, Hopkins L, Guth A, Dow S
Vet Comp Oncol
. 2018 Sep;
17(1):69-79.
PMID: 30238600
Cancer relapse following chemotherapy has been attributed in part to the presence of cancer stem cells (CSC), which drive tumour growth and metastasis and are highly resistant to the effects...
4.
Hartley G, Regan D, Guth A, Dow S
Cancer Immunol Immunother
. 2017 Feb;
66(4):523-535.
PMID: 28184968
PD-L1 is an immune checkpoint protein that has emerged as a major signaling molecule involved with tumor escape from T cell immune responses. Studies have shown that intra-tumoral expression of...