Gen Zheng
Overview
Explore the profile of Gen Zheng including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
341
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Recent Articles
1.
Pang S, Higgins G, Wiley J, Hou X, Lin R, Zheng G
Gastro Hep Adv
. 2024 Nov;
3(8):1116-1119.
PMID: 39529650
No abstract available.
2.
Hua X, Zhao C, Tian J, Wang J, Miao X, Zheng G, et al.
Elife
. 2024 Sep;
13.
PMID: 39320349
The β-catenin-dependent canonical Wnt signaling is pivotal in organ development, tissue homeostasis, and cancer. Here, we identified an upstream enhancer of - the coding gene for β-catenin, named ieCtnnb1 (ntestinal...
3.
Zheng G, Pang S, Wang J, Wang F, Wang Q, Yang L, et al.
iScience
. 2023 Jul;
26(7):107137.
PMID: 37404374
Stress-elevated glucocorticoids cause circadian disturbances and gut-brain axis (GBA) disorders, including irritable bowel syndrome (IBS). We hypothesized that the glucocorticoid receptor (GR/NR3C1) might cause chromatin circadian misalignment in the colon...
4.
Xu Y, Xiong Y, Liu Y, Li G, Bai T, Zheng G, et al.
Cell Biosci
. 2023 Jan;
13(1):7.
PMID: 36631841
Background: Our recent studies found that intestinal mechanical signals can regulate mucus synthesis and secretion of intestinal goblet cells through piezo type mechanosensitive ion channel component 1 (Piezo1), but the...
5.
Chen Y, Zhao R, Zheng G, Ling F, Li J, Xu M, et al.
Gastroenterol Rep (Oxf)
. 2022 Jun;
10:goac028.
PMID: 35720196
Delayed recovery from ulcerative colitis is mainly due to impaired healing of the intestinal epithelium after inflammation. The circadian rhythm controls cell proliferation and energy metabolism. However, the role of...
6.
Wiley J, Zong Y, Zheng G, Zhu S, Hong S
Neurogastroenterol Motil
. 2020 Aug;
32(12):e13941.
PMID: 32743845
Background: Chronic stress is associated with activation of the HPA axis, elevation in pro-inflammatory cytokines, decrease in intestinal epithelial cell tight junction (TJ) proteins, and enhanced visceral pain. It is...
7.
Kalinin A, Allyn-Feuer A, Ade A, Fon G, Meixner W, Dilworth D, et al.
Sci Rep
. 2018 Oct;
8(1):16142.
PMID: 30367081
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
8.
Zong Y, Zhu S, Zhang S, Zheng G, Wiley J, Hong S
Neurogastroenterol Motil
. 2018 Oct;
31(2):e13477.
PMID: 30284340
Background: Chronic psychological stress is associated with increased intestinal epithelial permeability and visceral hyperalgesia. Lubiprostone, an agonist for chloride channel-2, promotes secretion and accelerates restoration of injury-induced epithelial barrier dysfunction....
9.
Zheng G, Kalinin A, Dinov I, Meixner W, Zhu S, Wiley J
J Cell Mol Med
. 2018 Sep;
22(12):6380-6385.
PMID: 30255651
Colon crypts are recognized as a mechanical and biochemical Turing patterning model. Colon epithelial Caco-2 cell monolayer demonstrated 2D Turing patterns via force analysis of apical tight junction live cell...
10.
Kalinin A, Allyn-Feuer A, Ade A, Fon G, Meixner W, Dilworth D, et al.
Sci Rep
. 2018 Sep;
8(1):13658.
PMID: 30209281
Quantitative analysis of morphological changes in a cell nucleus is important for the understanding of nuclear architecture and its relationship with pathological conditions such as cancer. However, dimensionality of imaging...