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Gayathri Thillaiyampalam

Explore the profile of Gayathri Thillaiyampalam including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 130
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Recent Articles
1.
Bednarska K, Thillaiyampalam G, Mujaj S, Nourse J, Gunawardana J, Sabdia M, et al.
Acta Haematol . 2024 Mar; 147(6):676-691. PMID: 38479365
Introduction: Hodgkin lymphoma (HL) is deficient in major histocompatibility complex class I, rendering it susceptible to antitumoral immunity by natural killer (NK) cells. Despite the functional impairment of PD-1+ NK...
2.
Rantanen L, Bitar M, Lampinen R, Stewart R, Quek H, Oikari L, et al.
Cells . 2022 Oct; 11(20). PMID: 36291125
An early symptom of Alzheimer's disease (AD) is an impaired sense of smell, for which the molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived (ONS) cells from people...
3.
Murray L, Thillaiyampalam G, Xi Y, Cristino A, Upham J
Clin Transl Immunology . 2021 Dec; 10(11):e1356. PMID: 34868584
Objectives: Viral respiratory infections cause considerable morbidity and economic loss. While rhinoviruses (RV) typically cause little more than the common cold, they can produce severe infections and disease exacerbations in...
4.
Keane C, Law S, Gould C, Birch S, Sabdia M, de Long L, et al.
Blood Adv . 2020 Apr; 4(7):1367-1377. PMID: 32267932
Blockade of the PD-1 axis has modest efficacy in diffuse large B-cell lymphoma (DLBCL), but data regarding LAG3 are sparse. The impact of LAG3 digital gene expression was tested in...
5.
Cristino A, Nourse J, West R, Sabdia M, Law S, Gunawardana J, et al.
Blood . 2019 Dec; 134(25):2261-2270. PMID: 31856276
Epstein-Barr virus-positive (EBV+) diffuse large B-cell lymphomas (DLBCLs) express high levels of programmed death ligand 1 (PD-L1) and PD-L2. MicroRNA (miR) regulation is an important mechanism for the fine-tuning of...
6.
Cui Q, Vari F, Cristino A, Salomon C, Rice G, Sabdia M, et al.
Oncotarget . 2018 Nov; 9(78):34644-34657. PMID: 30410665
MicroRNA (miRNA)s are dysregulated in Diffuse large B-cell lymphoma (DLBCL), where they reflect the malignant B-cells and the immune infiltrate within the tumor microenvironment. There remains a paucity of data...
7.
Thillaiyampalam G, Liberante F, Murray L, Cardwell C, Mills K, Zhang S
BMC Bioinformatics . 2017 Dec; 18(1):581. PMID: 29268695
Background: Gene expression connectivity mapping has gained much popularity in recent years with a number of successful applications in biomedical research testifying its utility and promise. A major application of...
8.
Malcomson B, Wilson H, Veglia E, Thillaiyampalam G, Barsden R, Donegan S, et al.
Proc Natl Acad Sci U S A . 2016 Jun; 113(26):E3725-34. PMID: 27286825
Cystic fibrosis (CF) lung disease is characterized by chronic and exaggerated inflammation in the airways. Despite recent developments to therapeutically overcome the underlying functional defect in the cystic fibrosis transmembrane...