Gayan I Balasooriya
Overview
Explore the profile of Gayan I Balasooriya including associated specialties, affiliations and a list of published articles.
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5
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49
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Recent Articles
1.
Balasooriya G, Wee T, Spector D
bioRxiv
. 2023 Nov;
PMID: 37961255
Chromatin organization in the mammalian cell nucleus plays a vital role in the regulation of gene expression. The lamina-associated domain at the inner nuclear membrane has been shown to harbor...
2.
Balasooriya G, Spector D
bioRxiv
. 2023 Apr;
PMID: 37066204
Spatiotemporal gene regulation is fundamental to the biology of diploid cells. Therefore, effective communication between two alleles and their geometry in the nucleus is important. However, the mechanism that fine-tunes...
3.
Balasooriya G, Spector D
Nat Commun
. 2022 Oct;
13(1):5984.
PMID: 36216821
Each mammalian autosomal gene is represented by two alleles in diploid cells. To our knowledge, no insights have been made in regard to allele-specific regulatory mechanisms of autosomes. Here we...
4.
Balasooriya G, Goschorska M, Piddini E, Rawlins E
Development
. 2017 Mar;
144(9):1600-1606.
PMID: 28348168
Airway stem cells slowly self-renew and produce differentiated progeny to maintain homeostasis throughout the lifespan of an individual. Mutations in the molecular regulators of these processes may drive cancer or...
5.
Balasooriya G, Johnson J, Basson M, Rawlins E
Dev Cell
. 2016 Apr;
37(1):85-97.
PMID: 27046834
The steady-state airway epithelium has a low rate of stem cell turnover but can nevertheless mount a rapid proliferative response following injury. This suggests a mechanism to restrain proliferation at...