Gary W Mathern
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Explore the profile of Gary W Mathern including associated specialties, affiliations and a list of published articles.
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139
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8288
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Recent Articles
1.
Hauptman J, Antonios J, Mathern G, Levine M, Cepeda C
Cells
. 2025 Jan;
14(2).
PMID: 39851507
Abnormalities in the mammalian target of the rapamycin (mTOR) pathway have been implicated in numerous developmental brain disorders. While the molecular and histological abnormalities have been described, less is known...
2.
Zhang J, Argueta D, Tong X, Vinters H, Mathern G, Cepeda C
Front Cell Neurosci
. 2025 Jan;
18():1486315.
PMID: 39835291
Once believed to be the culprits of epileptogenic activity, the functional properties of balloon/giant cells (BC/GC), commonly found in some malformations of cortical development including focal cortical dysplasia type IIb...
3.
Weil A, Dimentberg E, Lewis E, Ibrahim G, Kola O, Tseng C, et al.
Epilepsia
. 2023 Jun;
65(1):46-56.
PMID: 37347512
Objectives: Although hemispheric surgeries are among the most effective procedures for drug-resistant epilepsy (DRE) in the pediatric population, there is a large variability in seizure outcomes at the group level....
4.
Kim Y, Kim Y, Lee H, So K, Choe Y, Suh B, et al.
Cell Rep
. 2023 Jan;
42(1):112003.
PMID: 36641749
Linear nevus sebaceous syndrome (LNSS) is a neurocutaneous disorder caused by somatic gain-of-function mutations in KRAS or HRAS. LNSS brains have neurodevelopmental defects, including cerebral defects and epilepsy; however, its...
5.
Phillips H, Chen J, Tucker A, Ding K, Kashanian A, Nagahama Y, et al.
Neurosurgery
. 2023 Jan;
92(2):300-307.
PMID: 36637266
Background: Cerebral hemispherectomy can effectively treat unihemispheric epilepsy. However, posthemispherectomy hydrocephalus (PHH), a serious life-long complication, remains prevalent, requiring careful considerations in technique selection and postoperative management. In 2016, we...
6.
Chung C, Yang X, Bae T, Vong K, Mittal S, Donkels C, et al.
Nat Genet
. 2023 Jan;
55(2):209-220.
PMID: 36635388
Malformations of cortical development (MCD) are neurological conditions involving focal disruptions of cortical architecture and cellular organization that arise during embryogenesis, largely from somatic mosaic mutations, and cause intractable epilepsy....
7.
Leitner D, Lin Z, Sawaged Z, Kanshin E, Friedman D, Devore S, et al.
Epilepsia
. 2022 Nov;
64(1):218-230.
PMID: 36336987
Objective: This study was undertaken to identify molecular mechanisms in brain tissue of Rasmussen encephalitis (RE) when compared to people with non-RE epilepsy (PWE) and control cases using whole exome...
8.
Ghochani Y, Muthukrishnan S, Sohrabi A, Kawaguchi R, Condro M, Bastola S, et al.
Cell Rep
. 2022 Oct;
41(3):111511.
PMID: 36261010
Glioblastoma (GBM) is characterized by extensive microvascular hyperproliferation. In addition to supplying blood to the tumor, GBM vessels also provide trophic support to glioma cells and serve as conduits for...
9.
Krawczyk M, Haney J, Pan L, Caneda C, Khankan R, Reyes S, et al.
J Neurosci
. 2022 Jan;
42(8):1587-1603.
PMID: 34987109
Astrocytes are critical for the development and function of synapses. There are notable species differences between human astrocytes and commonly used animal models. Yet, it is unclear whether astrocytic genes...
10.
Puka K, Jones M, Mathern G
Epilepsia
. 2021 Oct;
62(12):2932-2940.
PMID: 34608636
Objective: Hemispheric surgeries are an effective treatment option to control seizures for children with hemimegalencephaly (HME); however, not enough is known about their cognitive outcomes. This study aimed to delineate...