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Gary G Chen

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Articles 14
Citations 317
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Recent Articles
1.
Almeida D, Fiori L, Chen G, Aouabed Z, Lutz P, Zhang T, et al.
Psychoneuroendocrinology . 2021 Nov; 136:105600. PMID: 34839083
Childhood abuse significantly increases the lifetime risk of negative mental health outcomes. The oxytocinergic system, which plays a role in complex social and emotional behaviors, has been shown to be...
2.
Lutz P, Chay M, Pacis A, Chen G, Aouabed Z, Maffioletti E, et al.
Nat Commun . 2021 Feb; 12(1):1132. PMID: 33602921
Early-life adversity (ELA) is a major predictor of psychopathology, and is thought to increase lifetime risk by epigenetically regulating the genome. Here, focusing on the lateral amygdala, a major brain...
3.
Vaillancourt K, Yang J, Chen G, Yerko V, Theroux J, Aouabed Z, et al.
Mol Psychiatry . 2020 Oct; 26(7):3134-3151. PMID: 33046833
Epigenetic mechanisms, like those involving DNA methylation, are thought to mediate the relationship between chronic cocaine dependence and molecular changes in addiction-related neurocircuitry, but have been understudied in human brain....
4.
Gardini E, Chen G, Fiacco S, Mernone L, Willi J, Turecki G, et al.
Int J Mol Sci . 2020 May; 21(10). PMID: 32455834
Background Estrogen receptor α (ERα) contributes to maintaining biological processes preserving health during aging. DNA methylation changes of ERα gene () were established as playing a direct role in the...
5.
Mucha B, Banka S, Ajeawung N, Molidperee S, Chen G, Koenig M, et al.
Genet Med . 2019 Jan; 21(9):2159-2160. PMID: 30643220
The original version of this Article contained an error in the spelling of the author Siddharth Banka, which was incorrectly given as Siddhart Banka. This has now been corrected in...
6.
Mucha B, Banka S, Ajeawung N, Molidperee S, Chen G, Koenig M, et al.
Genet Med . 2018 Sep; 21(5):1058-1064. PMID: 30245510
Purpose: Contiguous gene deletions are known to cause several neurodevelopmental syndromes, many of which are caused by recurrent events on chromosome 16. However, chromosomal microarray studies (CMA) still yield copy-number...
7.
Chen G, Almeida D, Fiori L, Turecki G
Int J Neuropsychopharmacol . 2018 Jul; 21(10):895-900. PMID: 29986038
Background: The polyamines are a group of ubiquitous low-molecular-weight aliphatic molecules that play an essential role in various physiological functions of the mammalian CNS. Previous literature has indicated alterations in...
8.
Chen G, Gross J, Lutz P, Vaillancourt K, Maussion G, Bramoulle A, et al.
BMC Genomics . 2017 Jan; 18(1):96. PMID: 28100169
Background: Epigenetic modifications of DNA, such as 5-methylcytosine and 5-hydroxymethycytosine, play important roles in development and disease. Here, we present a cost-effective and versatile methodology for the analysis of DNA...
9.
Farmer W, Abrahamsson T, Chierzi S, Lui C, Zaelzer C, Jones E, et al.
Science . 2016 Feb; 351(6275):849-54. PMID: 26912893
Astrocytes are specialized and heterogeneous cells that contribute to central nervous system function and homeostasis. However, the mechanisms that create and maintain differences among astrocytes and allow them to fulfill...
10.
Gross J, Pacis A, Chen G, Barreiro L, Ernst C, Turecki G
BMC Genomics . 2015 Sep; 16:672. PMID: 26334641
Background: The recent discovery that methylated cytosines are converted to 5-hydroxymethylated cytosines (5hmC) by the family of ten-eleven translocation enzymes has sparked significant interest on the genomic location, the abundance...