Garry A Williams
Overview
Explore the profile of Garry A Williams including associated specialties, affiliations and a list of published articles.
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7
Citations
326
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Recent Articles
1.
Chan J, Glass G, Ersek A, Freidin A, Williams G, Gowers K, et al.
EMBO Mol Med
. 2015 Mar;
7(5):547-61.
PMID: 25770819
The mechanism by which trauma initiates healing remains unclear. Precise understanding of these events may define interventions for accelerating healing that could be translated to the clinical arena. We previously...
2.
Kennedy O, Sun H, Wu Y, Courtland H, Williams G, Cardoso L, et al.
Endocrinology
. 2014 Jan;
155(3):987-99.
PMID: 24424061
IGF-I is a critical regulator of skeletal acquisition, which acts in endocrine and autocrine/paracrine modes. In serum, IGF-I is carried by the IGF-binding proteins in binary complexes. Further stabilization of...
3.
Gong Z, Kennedy O, Sun H, Wu Y, Williams G, Klein L, et al.
Aging Cell
. 2013 Dec;
13(3):408-18.
PMID: 24341939
In lower or simple species, such as worms and flies, disruption of the insulin-like growth factor (IGF)-1 and the insulin signaling pathways has been shown to increase lifespan. In rodents,...
4.
Naot D, Williams G, Lin J, Cornish J, Grey A
Endocrinology
. 2012 Mar;
153(5):2076-81.
PMID: 22374965
Adiponectin, a hormone produced and secreted from adipose tissue, circulates at levels that are inversely related to visceral fat mass and bone mineral density. Adiponectin receptors are expressed in bone...
5.
Williams G, Callon K, Watson M, Costa J, Ding Y, Dickinson M, et al.
J Bone Miner Res
. 2011 Feb;
26(8):1698-709.
PMID: 21328476
Leptin, a major hormonal product of the adipocyte, regulates appetite and reproductive function through its hypothalamic receptors. The leptin receptor is present in osteoblasts and chondrocytes, and previously we have...
6.
Williams G, Wang Y, Callon K, Watson M, Lin J, Lam J, et al.
Endocrinology
. 2009 May;
150(8):3603-10.
PMID: 19406946
Fat mass impacts on both bone turnover and bone density and is a critical risk factor for osteoporotic fractures. Adipocyte-derived hormones may contribute to this relationship, and adiponectin is a...
7.
Cornish J, MacGibbon A, Lin J, Watson M, Callon K, Tong P, et al.
Endocrinology
. 2008 Jul;
149(11):5688-95.
PMID: 18617622
Clinical studies have shown that total body fat mass is related to both bone density and fracture risk and that fat ingestion reduces bone turnover. These effects are at least...