Ganesh Raj
Overview
Explore the profile of Ganesh Raj including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
817
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Recent Articles
1.
Xu Y, Wang Z, Sjostrom M, Deng S, Wang C, Johnson N, et al.
bioRxiv
. 2023 Nov;
PMID: 37961351
Statement Of Significance: This study reveals a novel epigenetic mechanism regulating tumor lineage plasticity and therapy response, enhances understanding of drug resistance and unveils a new therapeutic strategy for prostate...
2.
Li X, Wang Y, Deng S, Zhu G, Wang C, Johnson N, et al.
Cancer Cell
. 2023 Jul;
41(8):1427-1449.e12.
PMID: 37478850
Tumor mutational burden and heterogeneity has been suggested to fuel resistance to many targeted therapies. The cytosine deaminase APOBEC proteins have been implicated in the mutational signatures of more than...
3.
Gerald T, Raj G
Urol Clin North Am
. 2022 Oct;
49(4):603-614.
PMID: 36309417
Testosterone is a steroid hormone that is responsible for the development of normal male sexual characteristics and function as well as the maintenance of homeostasis among multiple organ systems throughout...
4.
Deng S, Wang C, Wang Y, Xu Y, Li X, Johnson N, et al.
Nat Cancer
. 2022 Oct;
3(10):1271.
PMID: 36241729
No abstract available.
5.
Deng S, Wang C, Wang Y, Xu Y, Li X, Johnson N, et al.
Nat Cancer
. 2022 Sep;
3(9):1071-1087.
PMID: 36065066
Emerging evidence indicates that various cancers can gain resistance to targeted therapies by acquiring lineage plasticity. Although various genomic and transcriptomic aberrations correlate with lineage plasticity, the molecular mechanisms enabling...
6.
Shah R, Palsgrove D, Desai N, Gagan J, Mennie A, Raj G, et al.
Mod Pathol
. 2022 May;
35(10):1468-1474.
PMID: 35606411
Locally relapsed prostate cancer (PCa) after radiation therapy (RT) is associated with substantial morbidity and mortality. Morphological and molecular consequences that may contribute to RT resistance and local recurrence remain...
7.
Lee K, Guerrero-Zotano A, Servetto A, Sudhan D, Lin C, Formisano L, et al.
Nat Commun
. 2020 Oct;
11(1):5488.
PMID: 33127913
The 17q23 amplicon is associated with poor outcome in ER breast cancers, but the causal genes to endocrine resistance in this amplicon are unclear. Here, we interrogate transcriptome data from...
8.
Costa D, Goldberg K, De Leon A, Lotan Y, Xi Y, Aziz M, et al.
Eur Urol Oncol
. 2019 Jul;
2(4):397-404.
PMID: 31277776
Background: With the increasing adoption of targeted prostate biopsies, it becomes important to understand the strengths and shortcomings of the techniques available for targeting suspicious lesions. Objective: To compare clinically...
9.
Lee C, Dang A, Hernandez E, Pong R, Chen B, Sonavane R, et al.
Oncogene
. 2019 Jun;
38(28):5580-5598.
PMID: 31152147
Gram-negative bacteria have been found to be a major population in prostatitis and prostate cancer (PCa) tissues. Lipopolysaccharide (LPS), a major compound of Gram-negative bacteria, with stimulatory activities in some...
10.
Shafi A, Schiewer M, de Leeuw R, Dylgjeri E, McCue P, Shah N, et al.
Eur Urol Oncol
. 2018 Nov;
1(4):325-337.
PMID: 30467556
Background: Androgen deprivation therapy is a first-line treatment for disseminated prostate cancer (PCa). However, virtually all tumors become resistant and recur as castration-resistant PCa, which has no durable cure. One...