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Gail E Johnson

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Articles 11
Citations 229
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Recent Articles
1.
Parikh S, Brownlee I, Robertson A, Manning N, Johnson G, Brodlie M, et al.
J Heart Lung Transplant . 2013 Feb; 32(4):418-23. PMID: 23384888
Background: Microaspiration after gastroesophageal reflux has been implicated in the chronic loss of allograft function in lung transplant patients. Bronchoalveolar lavage fluid (BALF) assessment for pepsin and bile salts is...
2.
Gardner A, Fisher A, Richter C, Johnson G, Moisey E, Brodlie M, et al.
Am J Pathol . 2012 Apr; 180(6):2293-308. PMID: 22525462
Therapies to limit or reverse fibrosis have proven unsuccessful, highlighting the need for a greater understanding of basic mechanisms that drive fibrosis and, in particular, the link between fibrosis and...
3.
Borthwick L, Botha P, Verdon B, Brodlie M, Gardner A, Bourn D, et al.
PLoS One . 2011 Aug; 6(8):e23226. PMID: 21826241
Background: Understanding where mutant CFTR is localised in airway epithelia is essential in guiding the best therapeutic approach to correct the dysfunction of the CFTR protein. The widely held paradigm...
4.
Brodlie M, McKean M, Johnson G, Gray J, Fisher A, Corris P, et al.
Am J Respir Crit Care Med . 2010 Apr; 182(3):369-75. PMID: 20395562
Rationale: Ceramide accumulates in the airway epithelium of mice deficient in cystic fibrosis transmembrane conductance regulator, resulting in susceptibility to Pseudomonas aeruginosa infection and inflammation. Objectives: To investigate quantitatively ceramide...
5.
Brodlie M, McKean M, Johnson G, Perry J, Nicholson A, Verdon B, et al.
Exp Lung Res . 2010 Mar; 36(2):101-10. PMID: 20205595
Lung disease is responsible for more than 95% of morbidity and mortality in cystic fibrosis. The exact pathogenesis of cystic fibrosis lung disease remains poorly understood. Experimental models are therefore...
6.
Murphy D, Forrest I, Corris P, Johnson G, Small T, Jones D, et al.
J Heart Lung Transplant . 2008 Oct; 27(11):1210-6. PMID: 18971093
Background: The bronchial epithelium is a source of mediators that may play a role in the airway inflammation and remodeling of post-transplant obliterative bronchiolitis (OB). Traditional strategies have failed to...
7.
Murphy D, Forrest I, Corris P, Johnson G, Small T, Jones D, et al.
Am J Physiol Lung Cell Mol Physiol . 2008 Jan; 294(3):L592-9. PMID: 18203812
Obliterative bronchiolitis (OB), the major cause of chronic lung allograft dysfunction, is characterized by airway neutrophilia, inflammation, and remodeling, with progressive fibroproliferation and obliteration of small airways that ultimately leads...
8.
Murphy D, Forrest I, Ward C, Corris P, Johnson G, Jones D, et al.
Thorax . 2007 Aug; 62(9):834. PMID: 17726173
No abstract available.
9.
Stovold R, Forrest I, Corris P, Murphy D, Smith J, Decalmer S, et al.
Am J Respir Crit Care Med . 2007 Apr; 175(12):1298-303. PMID: 17413126
Rationale: Human lung transplantation is a therapeutic option for selected patients with advanced cardiopulmonary disease, but long-term survival is limited by chronic rejection. Persistent acute rejection and gastric aspiration have...
10.
VanDyke M, Parker J, Smarr K, Hewett J, Johnson G, Slaughter J, et al.
Arthritis Rheum . 2004 Jun; 51(3):408-12. PMID: 15188326
Objective: To examine the level of anxiety experienced by individuals with rheumatoid arthritis (RA). Methods: Data from 2 previous studies were used to compare the level of anxiety (measured by...