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Gail C Brammar

Explore the profile of Gail C Brammar including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 239
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Recent Articles
1.
OBrien-Simpson N, Holden J, Lenzo J, Tan Y, Brammar G, Walsh K, et al.
NPJ Vaccines . 2017 Dec; 1:16022. PMID: 29263860
infected mice with an established -specific inflammatory immune response were protected from developing alveolar bone resorption by therapeutic vaccination with a chimera (KAS2-A1) immunogen targeting the major virulence factors of...
2.
OBrien-Simpson N, Burgess K, Brammar G, Darby I, Reynolds E
J Oral Microbiol . 2015 Sep; 7:29129. PMID: 26387647
Porphyromonas gingivalis is a key pathogen in the polymicrobial biofilm that is associated with the oral disease chronic periodontitis. A number of studies have shown that in humans the level...
3.
Lam R, OBrien-Simpson N, Hamilton J, Lenzo J, Holden J, Brammar G, et al.
Immunol Cell Biol . 2015 Mar; 93(8):705-15. PMID: 25753270
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and urokinase-type plasminogen activator (uPA) can contribute to the progression of chronic inflammatory diseases with possible involvement of macrophages. In this study, we investigated the role...
4.
Lam R, OBrien-Simpson N, Lenzo J, Holden J, Brammar G, Walsh K, et al.
J Immunol . 2014 Jul; 193(5):2349-62. PMID: 25070844
The role of the macrophage in the immunopathology of periodontitis has not been well defined. In this study, we show that intraoral inoculation of mice with Porphyromonas gingivalis resulted in...
5.
Pathirana R, OBrien-Simpson N, Brammar G, Slakeski N, Reynolds E
Infect Immun . 2007 Jan; 75(3):1436-42. PMID: 17220315
The contributions of three proteinase genes (rgpA, rgpB, and kgp) to the virulence of Porphyromonas gingivalis W50 were investigated in the murine periodontitis model. Mice were orally inoculated with eight...
6.
Osicka T, Forbes J, Thallas V, Brammar G, Jerums G, Comper W
Nephrology (Carlton) . 2004 Mar; 8(4):205-11. PMID: 15012722
This study has investigated the microtubular cytoskeleton in rat glomerular and proximal tubule cells in experimental diabetes. The effect of treatment with ramipril on the relationship between microtubule organization and...
7.
Osicka T, Russo L, Qiu M, Brammar G, Thallas V, Forbes J, et al.
J Hypertens . 2003 Dec; 21(12):2399-407. PMID: 14654761
Objective: This study examined the separate and combined effects of hypertension and diabetes on renal cortical expression of protein kinase C (PKC) isoforms -beta 1, -beta 2, -alpha and -epsilon,...
8.
Russo L, Brammar G, Jerums G, Comper W, Osicka T
J Hypertens . 2003 Feb; 21(2):419-28. PMID: 12569274
Objectives: Albumin excretion is modulated post-filtration by lysosomal processing that produces a spectrum of albumin-derived material in urine, much of which is not detected by conventional immunoassays. This study aimed...
9.
Russo L, Osicka T, Brammar G, Candido R, Jerums G, Comper W
Am J Nephrol . 2002 Dec; 23(2):61-70. PMID: 12481143
Background/aims: Recent studies show that albuminuria may be the result of changes in post-glomerular cellular uptake and processing of albumin. This study aims to determine whether this processing is disrupted...
10.
Forbes J, Cooper M, Thallas V, Burns W, Thomas M, Brammar G, et al.
Diabetes . 2002 Oct; 51(11):3274-82. PMID: 12401719
The effect of ACE inhibition on the formation of advanced glycation end products (AGEs) and oxidative stress was explored. Streptozocin-induced diabetic animals were randomized to no treatment, the ACE inhibitor...