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Gaetano Villani

Explore the profile of Gaetano Villani including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 962
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Recent Articles
1.
Arconzo M, Piccinin E, Pasculli E, Cariello M, Loiseau N, Bertrand-Michel J, et al.
Liver Int . 2024 Jul; 44(10):2738-2752. PMID: 39046166
Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is a growing cause of chronic liver disease, characterized by fat accumulation, inflammation and fibrosis, which development depends on mitochondrial dysfunction and oxidative...
2.
Piccinin E, Arconzo M, Pasculli E, Tricase A, Cultrera S, Bertrand-Michel J, et al.
Cell Biosci . 2024 Jun; 14(1):69. PMID: 38824560
Hepatocellular carcinoma (HCC) incidence is continuously increasing worldwide, due to the rise of metabolic dysfunction-associated steatohepatitis (MASH) cases. Cholesterol is an essential driver of the metabolic dysregulations that promote HCC...
3.
Piccinin E, Arconzo M, Matrella M, Cariello M, Polizzi A, Lippi Y, et al.
JHEP Rep . 2023 Oct; 5(11):100853. PMID: 37886435
Background & Aims: The gut-liver axis modulates the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), a spectrum of conditions characterised by hepatic steatosis and a progressive increase of inflammation...
4.
Cariello M, Piccinin E, Pasculli E, Arconzo M, Zerlotin R, DAmore S, et al.
Commun Biol . 2022 Jun; 5(1):553. PMID: 35672444
Several studies highlighted the importance of platelets in the tumor microenvironment due to their ability to interact with other cell types such as leukocytes, endothelial, stromal and cancer cells. Platelets...
5.
Garcia-Irigoyen O, Bovenga F, Piglionica M, Piccinin E, Cariello M, Arconzo M, et al.
iScience . 2022 Jan; 25(1):103707. PMID: 35036884
Compelling evidence support an involvement of oxidative stress and intestinal inflammation as early events in the predisposition and development of obesity and its related comorbidities. Here, we show that deficiency...
6.
Cariello M, Piccinin E, Zerlotin R, Piglionica M, Peres C, Divella C, et al.
Cancers (Basel) . 2021 Aug; 13(16). PMID: 34439397
Platelets represent the linkage between tissue damage and inflammatory response with a putative role in tumorigenesis. Given the importance of the microenvironment in colon cancer development, we elucidated the eventual...
7.
Battaglia S, De Santis S, Rutigliano M, Sallustio F, Picerno A, Frassanito M, et al.
Sci Rep . 2021 Jun; 11(1):12841. PMID: 34145306
Antibiotics that inhibit bacterial protein or nucleic acid synthesis and function can exert an off-target action on mitochondria (mitotoxic antibiotics), making actively dividing mammalian cells dependent on uridine and pyruvate...
8.
Contursi A, Arconzo M, Cariello M, Piglionica M, DAmore S, Vacca M, et al.
PLoS One . 2021 Apr; 16(4):e0249238. PMID: 33901189
The crypt-villus axis represents the essential unit of the small intestine, which integrity and functions are fundamental to assure tissue and whole-body homeostasis. Disruption of pathways regulating the fine balance...
9.
Piccinin E, Sardanelli A, Seibel P, Moschetta A, Cocco T, Villani G
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33800548
Parkinson's disease is one of the most common neurodegenerative disorders worldwide, characterized by a progressive loss of dopaminergic neurons mainly localized in the . In recent years, the detailed analyses...
10.
Cariello M, Contursi A, Gadaleta R, Piccinin E, De Santis S, Piglionica M, et al.
Nutrients . 2020 Apr; 12(4). PMID: 32295122
Inflammatory bowel disease (IBD) is a multifactorial intestinal disorder characterized by chronic intestinal inflammation. The etiology of IBD is still unclear, although genetic, environmental and host factors have been associated...