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Gael Petitjean

Explore the profile of Gael Petitjean including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 22
Citations 864
Followers 0
Related Specialties
Microbiology
Science
Infectious Diseases
Top 10 Co-Authors
Francoise Barre-Sinoussi
Yassine Al Tabaa
Beatrice Jacquelin
Anne-Sophie Liovat
Edouard Tuaillon
Jacques Reynes
Jean-Pierre Vendrell
Pierre Lebon
Michaela C Muller-Trutwin
Michaela Muller-Trutwin
Published In
AIDS
J Virol
PLoS Pathog
Nature
J Clin Virol
Affiliations
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Recent Articles
1.
Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome
Machida S, Depierre D, Chen H, Thenin-Houssier S, Petitjean G, Doyen C, et al.
Proc Natl Acad Sci U S A . 2020 Mar; 117(12):6822-6830. PMID: 32161134
The aim of the present study was to understand the biology of unintegrated HIV-1 DNA and reveal the mechanisms involved in its transcriptional silencing. We found that histones are loaded...
2.
Descours et al. reply
Descours B, Petitjean G, Benkirane M
Nature . 2018 Sep; 561(7723):E29. PMID: 30232426
No abstract available.
3.
Corrigendum: CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
Descours B, Petitjean G, Lopez-Zaragoza J, Bruel T, Raffel R, Psomas C, et al.
Nature . 2017 Jun; 546(7660):686. PMID: 28658234
This corrects the article DOI: 10.1038/nature21710.
4.
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
Descours B, Petitjean G, Lopez-Zaragoza J, Bruel T, Raffel R, Psomas C, et al.
Nature . 2017 Mar; 543(7646):564-567. PMID: 28297712
The persistence of the HIV reservoir in infected individuals is a major obstacle to the development of a cure for HIV. Here, using an in vitro model of HIV-infected quiescent...
5.
Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset
Ploquin M, Madec Y, Casrouge A, Huot N, Passaes C, Lecuroux C, et al.
PLoS Pathog . 2016 Aug; 12(8):e1005774. PMID: 27509048
Elevated blood CXCL10/IP-10 levels during primary HIV-1 infection (PHI) were described as an independent marker of rapid disease onset, more robust than peak viremia or CD4 cell nadir. IP-10 enhances...
6.
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection
Jochems S, Jacquelin B, Chauveau L, Huot N, Petitjean G, Lepelley A, et al.
J Virol . 2015 Apr; 89(13):6918-27. PMID: 25903334
Unlabelled: Human immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) lead to chronic inflammation and AIDS. Natural hosts, such as African green monkeys (AGM) and...
7.
Modulation of type I interferon-associated viral sensing during acute simian immunodeficiency virus infection in African green monkeys
Jochems S, Petitjean G, Kunkel D, Liovat A, Ploquin M, Barre-Sinoussi F, et al.
J Virol . 2014 Oct; 89(1):751-62. PMID: 25355871
Unlabelled: Natural hosts of simian immunodeficiency virus (SIV), such as African green monkeys (AGMs), do not progress to AIDS when infected with SIV. This is associated with an absence of...
8.
Phenotype alterations in regulatory T-cell subsets in primary HIV infection and identification of Tr1-like cells as the main interleukin 10-producing CD4+ T cells
Chevalier M, Didier C, Petitjean G, Karmochkine M, Girard P, Barre-Sinoussi F, et al.
J Infect Dis . 2014 Oct; 211(5):769-79. PMID: 25281758
Background: Conventional regulatory T cells (Tregs) can suppress human immunodeficiency virus type 1 (HIV-1)-specific immune responses but cannot control immune activation in primary HIV infection. Here, we characterized Treg subsets,...
9.
Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection
Jacquelin B, Petitjean G, Kunkel D, Liovat A, Jochems S, Rogers K, et al.
PLoS Pathog . 2014 Jul; 10(7):e1004241. PMID: 24991927
Chronic immune activation (IA) is considered as the driving force of CD4(+) T cell depletion and AIDS. Fundamental clues in the mechanisms that regulate IA could lie in natural hosts...
10.
The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation
Chevalier M, Petitjean G, Dunyach-Remy C, Didier C, Girard P, Manea M, et al.
PLoS Pathog . 2013 Jul; 9(6):e1003453. PMID: 23818854
Impairment of the intestinal barrier and subsequent microbial translocation (MT) may be involved in chronic immune activation, which plays a central role in HIV pathogenesis. Th17 cells are critical to...