Gabrielle A Hartley
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Explore the profile of Gabrielle A Hartley including associated specialties, affiliations and a list of published articles.
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14
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1576
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Recent Articles
1.
Hartley G, Okhovat M, Hoyt S, Fuller E, Pauloski N, Alexandre N, et al.
Cell Genom
. 2025 Mar;
:100808.
PMID: 40088887
Great apes have maintained a stable karyotype with few large-scale rearrangements; in contrast, gibbons have undergone a high rate of chromosomal rearrangements coincident with rapid centromere turnover. Here, we characterize...
2.
Hartley G, Okhovat M, Hoyt S, Fuller E, Pauloski N, Alexandre N, et al.
bioRxiv
. 2024 Sep;
PMID: 39257810
Great apes have maintained a stable karyotype with few large-scale rearrangements; in contrast, gibbons have undergone a high rate of chromosomal rearrangements coincident with rapid centromere turnover. Here we characterize...
3.
Yoo D, Rhie A, Hebbar P, Antonacci F, Logsdon G, Solar S, et al.
bioRxiv
. 2024 Aug;
PMID: 39131277
We present haplotype-resolved reference genomes and comparative analyses of six ape species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan, and siamang. We achieve chromosome-level contiguity with unparalleled sequence accuracy...
4.
Kalbfleisch T, McKay S, Murdoch B, Adelson D, Almansa-Villa D, Becker G, et al.
Nat Genet
. 2024 Aug;
56(8):1566-1573.
PMID: 39103649
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously 'invisible' parts of the genome and allow comparative analyses of complete genomes across entire clades. We...
5.
Makova K, Pickett B, Harris R, Hartley G, Cechova M, Pal K, et al.
Nature
. 2024 May;
630(8016):401-411.
PMID: 38811727
Apes possess two sex chromosomes-the male-specific Y chromosome and the X chromosome, which is present in both males and females. The Y chromosome is crucial for male reproduction, with deletions...
6.
Hartley G, Frankenberg S, Robinson N, MacDonald A, Hamede R, Burridge C, et al.
Commun Biol
. 2024 May;
7(1):636.
PMID: 38796620
The eastern quoll (Dasyurus viverrinus) is an endangered marsupial native to Australia. Since the extirpation of its mainland populations in the 20th century, wild eastern quolls have been restricted to...
7.
Brannan E, Hartley G, ONeill R
Genes (Basel)
. 2024 Jan;
15(1).
PMID: 38254952
Chromosome reshuffling events are often a foundational mechanism by which speciation can occur, giving rise to highly derivative karyotypes even amongst closely related species. Yet, the features that distinguish lineages...
8.
Makova K, Pickett B, Harris R, Hartley G, Cechova M, Pal K, et al.
bioRxiv
. 2023 Dec;
PMID: 38077089
Apes possess two sex chromosomes-the male-specific Y and the X shared by males and females. The Y chromosome is crucial for male reproduction, with deletions linked to infertility. The X...
9.
Rhie A, Nurk S, Cechova M, Hoyt S, Taylor D, Altemose N, et al.
Nature
. 2023 Aug;
621(7978):344-354.
PMID: 37612512
The human Y chromosome has been notoriously difficult to sequence and assemble because of its complex repeat structure that includes long palindromes, tandem repeats and segmental duplications. As a result,...
10.
Triant D, Walsh A, Hartley G, Petry B, Stegemiller M, Nelson B, et al.
Mamm Genome
. 2023 Jul;
34(3):418-436.
PMID: 37460664
Current genome sequencing technologies have made it possible to generate highly contiguous genome assemblies for non-model animal species. Despite advances in genome assembly methods, there is still room for improvement...