Gabriele H Marchler
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Explore the profile of Gabriele H Marchler including associated specialties, affiliations and a list of published articles.
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9006
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Recent Articles
1.
Wang J, Chitsaz F, Derbyshire M, Gonzales N, Gwadz M, Lu S, et al.
Nucleic Acids Res
. 2022 Dec;
51(D1):D384-D388.
PMID: 36477806
NLM's conserved domain database (CDD) is a collection of protein domain and protein family models constructed as multiple sequence alignments. Its main purpose is to provide annotation for protein and...
2.
Wang J, Youkharibache P, Marchler-Bauer A, Lanczycki C, Zhang D, Lu S, et al.
Front Mol Biosci
. 2022 Mar;
9:831740.
PMID: 35252351
iCn3D was initially developed as a web-based 3D molecular viewer. It then evolved from visualization into a full-featured interactive structural analysis software. It became a collaborative research instrument through the...
3.
Lu S, Wang J, Chitsaz F, Derbyshire M, Geer R, Gonzales N, et al.
Nucleic Acids Res
. 2019 Nov;
48(D1):D265-D268.
PMID: 31777944
As NLM's Conserved Domain Database (CDD) enters its 20th year of operations as a publicly available resource, CDD curation staff continues to develop hierarchical classifications of widely distributed protein domain...
4.
Wang J, Youkharibache P, Zhang D, Lanczycki C, Geer R, Madej T, et al.
Bioinformatics
. 2019 Jun;
36(1):131-135.
PMID: 31218344
Motivation: Build a web-based 3D molecular structure viewer focusing on interactive structural analysis. Results: iCn3D (I-see-in-3D) can simultaneously show 3D structure, 2D molecular contacts and 1D protein and nucleotide sequences...
5.
Haft D, DiCuccio M, Badretdin A, Brover V, Chetvernin V, ONeill K, et al.
Nucleic Acids Res
. 2017 Nov;
46(D1):D851-D860.
PMID: 29112715
The Reference Sequence (RefSeq) project at the National Center for Biotechnology Information (NCBI) provides annotation for over 95 000 prokaryotic genomes that meet standards for sequence quality, completeness, and freedom...
6.
Marchler-Bauer A, Bo Y, Han L, He J, Lanczycki C, Lu S, et al.
Nucleic Acids Res
. 2016 Dec;
45(D1):D200-D203.
PMID: 27899674
NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints. An archive of pre-computed...
7.
Derbyshire M, Gonzales N, Lu S, He J, Marchler G, Wang Z, et al.
Database (Oxford)
. 2015 Mar;
2015.
PMID: 25767294
When annotating protein sequences with the footprints of evolutionarily conserved domains, conservative score or E-value thresholds need to be applied for RPS-BLAST hits, to avoid many false positives. We notice...
8.
Marchler-Bauer A, Derbyshire M, Gonzales N, Lu S, Chitsaz F, Geer L, et al.
Nucleic Acids Res
. 2014 Nov;
43(Database issue):D222-6.
PMID: 25414356
NCBI's CDD, the Conserved Domain Database, enters its 15(th) year as a public resource for the annotation of proteins with the location of conserved domain footprints. Going forward, we strive...
9.
Marchler-Bauer A, Zheng C, Chitsaz F, Derbyshire M, Geer L, Geer R, et al.
Nucleic Acids Res
. 2012 Dec;
41(Database issue):D348-52.
PMID: 23197659
CDD, the Conserved Domain Database, is part of NCBI's Entrez query and retrieval system and is also accessible via http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml. CDD provides annotation of protein sequences with the location of...
10.
Marchler-Bauer A, Lu S, Anderson J, Chitsaz F, Derbyshire M, DeWeese-Scott C, et al.
Nucleic Acids Res
. 2010 Nov;
39(Database issue):D225-9.
PMID: 21109532
NCBI's Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from these footprints. CDD includes...