Gabriel Vargas
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Explore the profile of Gabriel Vargas including associated specialties, affiliations and a list of published articles.
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17
Citations
241
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Recent Articles
1.
Lodeweyckx T, de Hoon J, Van Laere K, Bautista E, Rizzo G, Bishop C, et al.
Br J Clin Pharmacol
. 2024 Jul;
90(10):2638-2651.
PMID: 38953404
Aims: Cerebral hypometabolism occurs years prior to a diagnosis of neurodegenerative diseases and coincides with reduced cerebral perfusion and declining noradrenergic transmission from the locus coeruleus. In pre-clinical models, β-adrenoceptor...
2.
Nussbaum J, Hussain A, Butera P, Ford A, Kitt M, ONeill E, et al.
J Clin Pharmacol
. 2024 Apr;
64(8):1023-1029.
PMID: 38651193
Gefapixant (MK-7264, RO4926219, AF-219) is a first-in-class P2X3 antagonists being developed to treat refractory or unexplained chronic cough. The initial single- and multiple-dose safety, tolerability, and pharmacokinetics of gefapixant at...
3.
Blanco-Meneses M, Serrano-Porras M, Calderon-Abarca A, Sebiani-Calvo A, Vargas G, Castro-Zuniga O
Microorganisms
. 2023 Nov;
11(11).
PMID: 38004744
Celery ( var. is affected by several plant diseases, such as f. sp. (Foa). Four Foa races have been found in the US. The goals of this study were to...
4.
Marynissen H, Buntinx L, Bamps D, Depre M, Ampe E, Van Hecken A, et al.
Clin Transl Sci
. 2022 May;
15(8):1968-1977.
PMID: 35621246
Maxadilan, a potent vasodilator peptide, selectively activates the PAC receptor, a promising target for migraine therapy. Therefore, maxadilan has been suggested as a tool to study the pharmacodynamics (PDs) of...
5.
Gavva N, Sandrock R, Arnold G, Davis M, Lamas E, Lindvay C, et al.
Sci Rep
. 2019 Dec;
9(1):19655.
PMID: 31873179
Multiple genome-wide association studies have identified non-coding single-nucleotide variants (SNVs) near (e.g., rs10166942[C]) or within (rs17862920[T]) the TRPM8 gene that encodes a cold thermosensor is associated with reduced migraine risk....
6.
Fernandez-Gajardo R, Matamala J, Gutierrez R, Lozano P, Cortes-Fuentes I, Sotomayor C, et al.
PLoS One
. 2019 Jul;
14(7):e0219402.
PMID: 31295304
Introduction: Uric acid has gained considerable attention as a potential neuroprotective agent in stroke during the last decades, however, its role in the pathophysiology of ischemic stroke remains poorly understood....
7.
Abarca J, Vargas G, Zuniga I, Whitfield S, Woodhams D, Kerby J, et al.
Front Microbiol
. 2018 Sep;
9:2001.
PMID: 30233511
Amphibian skin is a suitable environment for rich communities of microorganisms, both beneficial and detrimental to the host. The amphibian cutaneous microbiota has been hypothesized to play an important role...
8.
Reyes S P, Badilla O L, Andreu D, Besa V, Rivera R, Sordo G, et al.
Rev Med Chil
. 2018 Aug;
146(6):708-716.
PMID: 30148902
Background: Recently, five randomized controlled trials confirmed the efficacy and safety of endovascular treatment with or without intravenous thrombolysis in acute ischemic stroke with large-vessel occlusion. Aim: To report patients...
9.
Gold M, Amatniek J, Carrillo M, Cedarbaum J, Hendrix J, Miller B, et al.
Alzheimers Dement (N Y)
. 2018 Jun;
4:234-242.
PMID: 29955666
Digital technology is transforming the development of drugs for Alzheimer's disease and was the topic of the Alzheimer's Association's Research Roundtable on its May 23-24, 2017 meeting. Research indicates that...
10.
de Hoon J, Van Hecken A, Vandermeulen C, Herbots M, Kubo Y, Lee E, et al.
Cephalalgia
. 2018 May;
39(1):100-110.
PMID: 29783863
Objectives: The aim of this study was to assess the effects of concomitant administration of erenumab and sumatriptan on resting blood pressure, pharmacokinetics, safety, and tolerability in healthy subjects. Methods:...