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Gabor Petho

Explore the profile of Gabor Petho including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 527
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Recent Articles
1.
Borbely E, Petho G
Curr Opin Pharmacol . 2024 Aug; 77:102474. PMID: 39121555
Neuropeptides, including tachykinins, CGRP, and somatostatin, are localized in a peptidergic subgroup of nociceptive primary afferent neurons. Tachykinins and CGRP are pronociceptive, somatostatin is an antinociceptive mediator. Intensive drug research...
2.
Petho G, Kantas B, Horvath A, Pinter E
Int J Mol Sci . 2023 Dec; 24(24). PMID: 38138971
Epigenetics deals with alterations to the gene expression that occur without change in the nucleotide sequence in the DNA. Various covalent modifications of the DNA and/or the surrounding histone proteins...
3.
Pinter E, Helyes Z, Szoke E, Bolcskei K, Kecskes A, Petho G
Temperature (Austin) . 2023 Dec; 10(1):13-34. PMID: 38059854
This paper is dedicated to the memory of János Szolcsányi (1938-2018), an outstanding Hungarian scientist. Among analgesics that act on pain receptors, he identified capsaicin as a selective lead molecule....
4.
Kantas B, Szoke E, Borzsei R, Banhegyi P, Asghar J, Hudhud L, et al.
Front Pharmacol . 2021 Apr; 11:601887. PMID: 33815096
Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via its receptor subtype 4 (SST) without influencing endocrine functions. Therefore, SST is considered to be a novel...
5.
Kriszta G, Kriszta Z, Vancsa S, Hegyi P, Frim L, Eross B, et al.
Front Pharmacol . 2021 Mar; 12:619524. PMID: 33762942
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus disease 2019 (COVID-19), caused the outbreak escalated to pandemic. Reports suggested that near 1-3% of COVID-19 cases have a...
6.
Eross B, Molnar Z, Szakacs Z, Zadori N, Szako L, Vancsa S, et al.
Trials . 2020 Sep; 21(1):809. PMID: 32993779
Background: Early reports indicate that COVID-19 may require intensive care unit (ICU) admission in 5-26% and overall mortality can rise to 11% of the recognised cases, particularly affecting the elderly....
7.
Mohos V, Panovics A, Fliszar-Nyul E, Schilli G, Hetenyi C, Mladenka P, et al.
Int J Mol Sci . 2019 Jun; 20(11). PMID: 31159151
Quercetin is an abundant flavonoid in nature and is used in several dietary supplements. Although quercetin is extensively metabolized by human enzymes and the colonic microflora, we have only few...
8.
Fliszar-Nyul E, Lemli B, Kunsagi-Mate S, Dellafiora L, DallAsta C, Cruciani G, et al.
Int J Mol Sci . 2019 May; 20(9). PMID: 31083629
Alternariol (AOH) is a mycotoxin produced by species. In vitro studies suggest the genotoxic, mutagenic, and endocrine disruptor effects of AOH, and an increased incidence of esophageal cancer has been...
9.
Petho G, Bolcskei K, Furedi R, Botz B, Bagoly T, Pinter E, et al.
Neuropeptides . 2017 Mar; 62:1-10. PMID: 28291541
Stimulation of capsaicin-sensitive peripheral sensory nerve terminals induces remote anti-inflammatory effects throughout the body of anesthetized rats and guinea-pigs mediated by somatostatin. As somatostatin has also antinociceptive effects, the study...
10.
Tekus V, Horvath A, Hajna Z, Borbely E, Bolcskei K, Boros M, et al.
Life Sci . 2016 Apr; 154:66-74. PMID: 27126699
Aims: To investigate the roles of TRPV1 and TRPA1 channels in baseline and allyl isothiocyanate (AITC)-evoked nociceptive responses by comparing wild-type and gene-deficient mice. Main Methods: In contrast to conventional...