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Gabor B Brenner

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Articles 18
Citations 238
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Recent Articles
11.
Pajovic V, Kovacshazi C, Kosic M, Vasic M, dukic L, Brenner G, et al.
Toxicol Appl Pharmacol . 2021 May; 423:115579. PMID: 34015281
Cardiomyopathy resistant to treatment is the most serious adverse effect of doxorubicin (dox). The mechanisms of dox-induced cardiomyopathy (DCM) have been extensively studied in dilated forms of DCM. However, efficient...
12.
Brenner G, Giricz Z, Garamvolgyi R, Makkos A, Onodi Z, Sayour N, et al.
J Vis Exp . 2021 May; (170). PMID: 33938885
The development of heart failure is the most powerful predictor of long-term mortality in patients surviving acute myocardial infarction (MI). There is an unmet clinical need for prevention and therapy...
13.
Pecan P, Hambalko S, Ha V, Nagy C, Pelyhe C, Lainscek D, et al.
Int J Mol Sci . 2020 Oct; 21(20). PMID: 33081396
Cardioprotection against ischemia/reperfusion injury is still an unmet clinical need. The transient activation of Toll-like receptors (TLRs) has been implicated in cardioprotection, which may be achieved by treatment with blood-derived...
14.
Laszlo S, Lazar B, Brenner G, Makkos A, Balogh M, Al-Khrasani M, et al.
Biochem Pharmacol . 2020 Jun; 178:114099. PMID: 32540483
There is some recent evidence that cardiac ischemia/reperfusion (I/R) injury induces intestinal damage within days, which contributes to adverse cardiovascular outcomes after myocardial infarction. However, it is not clear whether...
15.
Szotak-Ajtay K, Szoke D, Kovacs G, Andreka J, Brenner G, Giricz Z, et al.
Front Bioeng Biotechnol . 2020 Mar; 8:136. PMID: 32211389
Embryonic lungs must be inflated immediately after birth to establish respiration. In addition to pulmonary surfactant, recently, we have revealed lymphatic function as a previously unknown regulator of prenatal lung...
16.
Brenner G, Makkos A, Nagy C, Onodi Z, Sayour N, Gergely T, et al.
Cells . 2020 Mar; 9(3). PMID: 32111102
Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market. The novel concept of 'hidden cardiotoxicity' is defined...
17.
Lazar B, Brenner G, Makkos A, Balogh M, Laszlo S, Al-Khrasani M, et al.
Cells . 2019 Mar; 8(3). PMID: 30884758
Intestinal dysbiosis is linked to numerous gastrointestinal disorders, including inflammatory bowel diseases. It is a question of debate if coxibs, selective inhibitors of cyclooxygenase (COX)-2, cause dysbiosis. Therefore, in the...
18.
Onodi Z, Pelyhe C, Nagy C, Brenner G, Almasi L, Kittel A, et al.
Front Physiol . 2018 Nov; 9:1479. PMID: 30405435
Extracellular vesicles (EVs) (isolated from blood plasma) are currently being extensively researched, both as biomarkers and for their therapeutic possibilities. One challenging aspect to this research is the efficient isolation...