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G Tsirakis

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Articles 16
Citations 155
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Recent Articles
1.
Kokonozaki M, Tsirakis G, Devetzoglou M, Kyriakaki S, Antonakis A, Vyzoukaki R, et al.
Leuk Res . 2015 Nov; 39(12):1467-72. PMID: 26521986
The aim of the study was to evaluate serum levels of FLT3-ligand (FLT3-L), a soluble molecule in bone marrow (BM), participating actively in hematopoiesis, in relation with angiogenic factors in...
2.
Alexandrakis M, Pappa C, Kokonozaki M, Boula A, Vyzoukaki R, Staphylaki D, et al.
Med Oncol . 2015 Jan; 32(3):42. PMID: 25631632
Angiogenesis is an important hallmark in multiple myeloma (MM) pathogenesis, with the participation of various versatile molecules. Interleukin-20 (IL-20) is a pro-inflammatory cytokine with diverse angiogenic properties. Our purpose was...
3.
Pappa C, Tsirakis G, Devetzoglou M, Zafeiri M, Vyzoukaki R, Androvitsanea A, et al.
Tumour Biol . 2014 Feb; 35(6):5647-51. PMID: 24563338
Angiogenesis is a crucial process in growth and progression of multiple myeloma (MM). Mast cells (MCs) play an important role in MM angiogenesis. Various angiogenic mediators secreted by MCs regulate...
4.
Pappa C, Alexandrakis M, Boula A, Psarakis F, Kolovou A, Bantouna V, et al.
Hematol Oncol . 2013 Apr; 31(4):201-5. PMID: 23576184
Angiogenesis is an essential process for the expansion of multiple myeloma (MM), in which many angiogenic factors participate. Endoglin (CD105) is a transforming growth factor-β co-receptor, being mainly expressed in...
5.
Pappa C, Tsirakis G, Psarakis F, Kolovou A, Tsigaridaki M, Stafylaki D, et al.
Med Oncol . 2012 Dec; 30(1):363. PMID: 23266941
There are many growth factors influencing the expansion of multiple myeloma (MM). Angiogenesis is a process that may enhance MM growth, in various manners. Among them, insulin-like growth factor-1 (IGF-1)...
6.
Tsirakis G, Pappa C, Spanoudakis M, Chochlakis D, Alegakis A, Psarakis F, et al.
Eur J Intern Med . 2012 May; 23(4):368-73. PMID: 22560388
Background: Τhe importance of angiogenesis in malignancies' growth is well recognized. CD105 (Endoglin), a proliferation-associated glycoprotein, is a powerful marker of neovascularization. Elevated amounts of soluble CD105 (sCD105) have been...
7.
Fragioudaki M, Boula A, Tsirakis G, Psarakis F, Spanoudakis M, Papadakis I, et al.
Ann Hematol . 2012 Apr; 91(9):1413-8. PMID: 22526370
B cell-activating factor (BAFF) is a cytokine that plays a major role in the maintenance of normal B-cell development and homeostasis. It has been suggested that in multiple myeloma (MM)...
8.
Fragioudaki M, Tsirakis G, Pappa C, Aristeidou I, Tsioutis C, Alegakis A, et al.
Leuk Res . 2012 Apr; 36(8):1004-8. PMID: 22498341
B-cell activating factor (BAFF) is a B-cell growth factor. We measured its serum levels and correlated them with parameters of disease activity, as serum levels of tumor necrosis factor-α and...
9.
Tsirakis G, Pappa C, Psarakis F, Fragioudaki M, Tsioutis C, Stavroulaki E, et al.
Med Oncol . 2012 Mar; 29(4):2396-401. PMID: 22403003
Multiple myeloma (MM) is a disease of plasma cells that express the CD40 receptor. Binding of the CD40 by its natural ligand, CD40 ligand (CD40L), produces growth arrest and/or apoptosis...
10.
Tsirakis G, Pappa C, Kaparou M, Katsomitrou V, Hatzivasili A, Alegakis T, et al.
Eur J Histochem . 2011 Nov; 55(3):e21. PMID: 22073368
Multiple myeloma (MM) is a malignant plasma cell disease. Several proinflammatory cytokines produced by malignant plasma cells and bone marrow (BM) stromal cells are involved in the pathogenesis of the...