G Stephanopoulos
Overview
Explore the profile of G Stephanopoulos including associated specialties, affiliations and a list of published articles.
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Articles
94
Citations
1515
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Recent Articles
1.
Abdel-Mawgoud A, Stephanopoulos G
Metab Eng
. 2020 Aug;
62:106-115.
PMID: 32758536
Yarrowia lipolytica is an important oleaginous yeast currently used in the production of specialty chemicals and has a great potential for further applications in lipid biotechnology. Harnessing the full potential...
2.
Vasdekis A, Alanazi H, Silverman A, Williams C, Canul A, Cliff J, et al.
Nat Commun
. 2019 Feb;
10(1):848.
PMID: 30783105
Optimal metabolic trade-offs between growth and productivity are key constraints in strain optimization by metabolic engineering; however, how cellular noise impacts these trade-offs and drives the emergence of subpopulations with...
3.
Zhou K, Edgar S, Stephanopoulos G
Methods Enzymol
. 2016 Jul;
575:225-45.
PMID: 27417931
Humans constantly look for faster, more economical, and more sustainable ways to produce chemicals that originally harvested from nature. Over the past two decades, substantial progress has been made toward...
4.
Vasdekis A, Silverman A, Stephanopoulos G
Sci Rep
. 2015 Dec;
5:17689.
PMID: 26657999
Bioprocess limitations imposed by microbial cell-to-cell phenotypic diversity remain poorly understood. To address this, we investigated the origins of such culture diversity during lipid production and assessed the impact of...
5.
Vander Heiden M, Lunt S, Dayton T, Fiske B, Israelsen W, Mattaini K, et al.
Cold Spring Harb Symp Quant Biol
. 2012 Jan;
76:325-34.
PMID: 22262476
Proliferating cells adapt metabolism to support the conversion of available nutrients into biomass. How cell metabolism is regulated to balance the production of ATP, metabolite building blocks, and reducing equivalents...
6.
Kornfield J, Stephanopoulos G, Voecks G
Biotechnol Prog
. 2010 Jun;
2(2):98-104.
PMID: 20568196
A novel bioreactor concept is described for facilitated gas-liquid mass transfer, specifically oxygen supply, at low shear rates and low power input. The cross flow monolithic reactor is a single...
7.
Davison B, San K, Stephanopoulos G
Biotechnol Prog
. 2010 Jun;
1(4):260-9.
PMID: 20568174
A reactor with size-selective properties was found to allow a mixed culture of Escherichia coli and Saccharomyces cerevisiae to coexist under continuous culture conditions. The reactor consisted of a fermentor...
8.
Stephanopoulos G, San K, Davison B
Biotechnol Prog
. 2010 Jun;
1(4):250-9.
PMID: 20568173
A novel bioreactor design has been investigated for carrying out in a single unit a fermentation and cell recycle process simultaneously. The reactor consisted of a typical fermentor and a...
9.
Reinecke M, Stephanopoulos G
Cytotechnology
. 2008 Nov;
34(3):237-42.
PMID: 19003399
A flow injection analysis (FIA) system is presented for a twostep immunoassay-based determination of the total humanprolactin (hPRL) concentration along with its degree ofglycosylation. Separate measurement of total hPRL and...
10.
Park S, Sinskey A, Stephanopoulos G
Biotechnol Bioeng
. 2008 Jul;
55(6):864-79.
PMID: 18636597
The physiology and central carbon metabolism of Corynebacterium glutamicum was investigated through the study of specific disruption mutants. Mutants deficient in phosphoenolpyruvate carboxylase (PPC) and/or pyruvate kinase (PK) activity were...