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G Rappl

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Articles 21
Citations 454
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Recent Articles
1.
Oberbeck S, Schrader A, Warner K, Jungherz D, Crispatzu G, von Jan J, et al.
Blood . 2020 Dec; 136(24):2786-2802. PMID: 33301031
T-cell prolymphocytic leukemia (T-PLL) is a poor-prognostic neoplasm. Differentiation stage and immune-effector functions of the underlying tumor cell are insufficiently characterized. Constitutive activation of the T-cell leukemia 1A (TCL1A) oncogene...
2.
Rohrig G, Rappl G, Vahldick B, Kaul I, Schulz R
Z Gerontol Geriatr . 2013 Jun; 47(1):51-6. PMID: 23743883
Background: Iron deficiency anemia (IDA) and anemia of chronic diseases (ACD) are common in the geriatric population. However, differentiation between IDA and ACD is still problematic. Hepcidin is a key...
3.
Chmielewski M, Rappl G, Hombach A, Abken H
Gene Ther . 2012 Mar; 20(2):177-86. PMID: 22378346
A majority of cancer deaths are because of an uncontrolled relapse of the disease despite initial remission after therapy, asking for strategies to control tumour cells in the long term....
4.
Laudes M, Oberhauser F, Schulte D, Freude S, Bilkovski R, Mauer J, et al.
Horm Metab Res . 2010 Jan; 42(4):268-73. PMID: 20091460
Low-grade inflammation is important in the development of obesity related pathologies such as insulin resistance and type 2 diabetes, and also cardiovascular disease. Visfatin/PBEF/Nampt and resistin are proinflammatory adipokines secreted...
5.
Hombach A, Kofler D, Rappl G, Abken H
Gene Ther . 2009 Jun; 16(9):1088-96. PMID: 19554034
Recent insight into the balance of self-tolerance and auto-aggression has raised interest in using human regulatory T (Treg) cells for adoptive immunotherapy of unlimited autoimmune diseases including type-1 diabetes, rhematoid...
6.
Rossler M, Rappl G, Muche M, Hasselmann D, Sterry W, Tilgen W, et al.
Clin Microbiol Infect . 2003 Aug; 9(7):721-3. PMID: 12925116
Recently, Chlamydia pneumoniae-specific DNA and antigens were reported in the skin of patients with Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphomas. In order to revalidate these...
7.
Rappl G, Abken H, Muche J, Sterry W, Tilgen W, Andre S, et al.
Leukemia . 2002 May; 16(5):840-5. PMID: 11986945
In early stages of cutaneous T cell lymphoma (Sézary syndrome) both CD4+CD7- and CD4+CD7+ T cells clonally expand whereas in late stages of the disease CD7- cells are predominant in...
8.
Rappl G, Hasselmann D, Rossler M, Ugurel S, Tilgen W, Reinhold U
Ann N Y Acad Sci . 2001 Nov; 945:189-91. PMID: 11708477
It has been suggested that extracellular mRNA might be released from tumor cells and might be protected from serum RNase by proteins or proteolipid complexes. Our group has recently assessed...
9.
Rappl G, Abken H, Hasselmann D, Tilgen W, Ugurel S, Reinhold U
Cell Death Differ . 2001 Sep; 8(4):395-402. PMID: 11550091
The CD7(-) subset of CD4(+) T cells reflects a stable differentiation state of post-thymic helper T cells with CD45R0(+)CD45RA(-) 'memory' phenotype. Here we report that CD4(+)CD7(-) T cells are prone...
10.
Hasselmann D, Rappl G, Tilgen W, Reinhold U
Clin Chem . 2001 Jul; 47(8):1488-9. PMID: 11468248
No abstract available.