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G Rainaldi

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Articles 103
Citations 824
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Recent Articles
11.
Calcabrini A, Rainaldi G, Santini M
J Mater Sci Mater Med . 2004 Sep; 10(10/11):613-20. PMID: 15347975
We have recently demonstrated that if human K562 erythroleukaemic cells, which normally grow in suspension, are grown on a positively-charged surface composed of polylysine, a transient reorganization of CD54 (ICAM-1),...
12.
Poliseno L, Mercatanti A, Citti L, Rainaldi G
Curr Pharm Biotechnol . 2004 Aug; 5(4):361-8. PMID: 15320767
RNA interference consists of a sequence specific post-transcriptional gene silencing phenomenon triggered by a double strand RNA molecule homologous to the silenced gene. The dsRNA is cleaved by DICER enzyme...
13.
Citti L, Rovero P, Colombo M, Mariani L, Poliseno L, Rainaldi G
Biotechniques . 2002 Jan; 32(1):172-4, 176-7. PMID: 11808690
We investigated the ability of an amphipathic oligopeptide to carry a synthetic dsDNA oligonucleotide inside human cells. The oligonucleotide was designed as a decoy binding site for the transcriptional activator...
14.
Colombo M, Citti L, Basta G, De Caterina R, Biagini A, Rainaldi G
Cardiovasc Drugs Ther . 2001 Aug; 15(1):25-9. PMID: 11504160
Vascular endothelium gene expression regulates blood-vessel wall interactions, vascular permeability, smooth muscle cell growth and tone. The possibility to introduce exogenous DNA or RNA sequences in endothelial cells represents a...
15.
Rainaldi G, Filippini P, Ferrante A, Indovina P, Santini M
J Biomed Mater Res . 2001 Jun; 55(1):104-13. PMID: 11426387
The role of protein adsorption in the forced adhesive growth of K562 leukemic cells onto a cationic surface composed of polylysine was investigated. Numerous studies have demonstrated that adhesion in...
16.
Santini M, Romano R, Rainaldi G, Filippini P, Bravo E, Porcu L, et al.
Biochim Biophys Acta . 2001 Mar; 1531(1-2):111-31. PMID: 11278177
The high resolution proton nuclear magnetic resonance (1H-NMR) spectra of two different cell lines exhibiting multidrug resistance (MDR) as demonstrated by the expression of the well-known energy-driven, membrane-bound 170 kDa...
17.
Filippini P, Rainaldi G, Ferrante A, Mecheri B, Gabrielli G, Bombace M, et al.
J Biomed Mater Res . 2001 Mar; 55(3):338-49. PMID: 11255187
The effects of growing the Saos-2 human osteosarcoma cell line onto surfaces containing -CH(3), -OH, -COOH, -NH(2), and C6H5 groups obtained by silane modification were examined. These cells were used...
18.
Santini M, Rainaldi G, Indovina P
Int J Radiat Biol . 2001 Feb; 75(7):787-99. PMID: 10489890
Purpose: Multicellular tumour spheroids are being used with increasing frequency in various aspects of tumour biology, including studies dealing with radiation biology. This review attempts to outline recent studies using...
19.
Santini M, Rainaldi G, Indovina P
Crit Rev Oncol Hematol . 2000 Oct; 36(2-3):75-87. PMID: 11033298
In the last few years, it has become increasingly apparent that cell survival and death, especially apoptosis, strongly depend on cell adhesion and the extracellular matrix. In addition, it has...
20.
Mariani L, Citti L, Nevischi S, Eckstein F, Rainaldi G
Cancer Gene Ther . 2000 Jul; 7(6):905-9. PMID: 10880022
N-alkyl-nitrosoureas and alkyl-triazenes are alkylating antineoplastic drugs, the efficacy of which is strongly affected by the level of expression of the DNA-repair enzyme O6-methylguanine-DNA methyltransferase (MGMT). In tumors, MGMT activity...