G R Ferrier
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Explore the profile of G R Ferrier including associated specialties, affiliations and a list of published articles.
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68
Citations
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Recent Articles
1.
Safari E, Fogarty N, Ferrier G, Hopkins L, Gilmour A
Meat Sci
. 2011 Nov;
57(2):153-9.
PMID: 22061358
The effect of genotype on eating quality was evaluated on m. Longissimus thoracis et lumborum (LTL) muscle of 60 lambs. The lambs were sired by a selection of Texel (T),...
2.
Xiong W, Moore H, Howlett S, Ferrier G
J Pharmacol Exp Ther
. 2001 Aug;
298(3):954-63.
PMID: 11504790
The objective of this study was to determine whether the voltage-sensitive release mechanism (VSRM) can be stimulated independently from Ca(2+)-induced Ca(2+) release (CICR) by drugs that elevate intracellular cAMP. Contractions...
3.
Ferrier G, Howlett S
Am J Physiol Heart Circ Physiol
. 2001 Apr;
280(5):H1928-44.
PMID: 11299192
The steps that couple depolarization of the cardiac cell membrane to initiation of contraction remain controversial. Depolarization triggers a rise in intracellular free Ca(2+) which activates contractile myofilaments. Most of...
4.
Louch W, Ferrier G, Howlett S
J Pharmacol Exp Ther
. 2000 Oct;
295(2):697-704.
PMID: 11046108
Losartan, a selective angiotensin II (AII) type I receptor antagonist, may protect against myocardial stunning and arrhythmia in ischemia and reperfusion. To examine the cellular basis for these protective actions,...
5.
Zhu J, Ferrier G
Am J Physiol Heart Circ Physiol
. 2000 Oct;
279(5):H2104-15.
PMID: 11045943
A role for Ca(2+)-calmodulin-dependent kinase (CamK) in regulation of the voltage-sensitive release mechanism (VSRM) was investigated in guinea pig ventricular myocytes. Voltage clamp was used to separate the VSRM from...
6.
Ferrier G, Redondo I, Mason C, Mapplebeck C, Howlett S
Am J Physiol Heart Circ Physiol
. 2000 Apr;
278(5):H1618-26.
PMID: 10775142
Control of contraction and relaxation by membrane potential was investigated in voltage-clamped guinea pig ventricular myocytes at 37 degrees C. Depolarization initiated phasic contractions, followed by sustained contractions that relaxed...
7.
Denovan-Wright E, Ferrier G, Robertson H, Howlett S
Biochem Biophys Res Commun
. 2000 Jan;
267(1):103-8.
PMID: 10623582
Cardiomyopathic (CM) hamsters have a disruption in the delta-sarcoglycan gene which leads to progressive cardiac necrosis by 30 to 40 days of age, hypertrophy by 120 days, and heart failure...
8.
Howlett S, Xiong W, Mapplebeck C, Ferrier G
Am J Physiol
. 1999 Nov;
277(5):H1690-700.
PMID: 10564121
We investigated excitation-contraction (EC) coupling in isolated ventricular myocytes from prehypertrophic cardiomyopathic (CM) hamster hearts. Conventional and voltage-clamp recordings were made with high-resistance microelectrodes, and cell shortening was measured with...
9.
Mason C, Ferrier G
J Physiol
. 1999 Aug;
519 Pt 3:851-65.
PMID: 10457096
1. Effects of tetracaine on membrane currents and cell shortening were measured with high resistance electrodes, single-electrode voltage clamp (switch clamp) and a video edge detector at 37 C in...
10.
Ferrier G, Zhu J, Redondo I, Howlett S
J Physiol
. 1998 Oct;
513 ( Pt 1):185-201.
PMID: 9782169
1. Ionic currents and unloaded cell shortening were recorded from guinea-pig ventricular myocytes with single electrode voltage clamp techniques and video edge detection at 37 C. Patch pipettes (1-3 MOmega)...