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G Muccioli

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Articles 91
Citations 1248
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Recent Articles
1.
Broglio F, Prodam F, Riganti F, Gottero C, Destefanis S, Granata R, et al.
J Endocrinol Invest . 2008 Nov; 31(9):788-94. PMID: 18997491
Context: Acylated ghrelin (AG) has been discovered as a natural ligand of the GH secretagogue receptor type 1a and is now recognized as an important orexigenic factor. Besides stimulation of...
2.
Volante M, Rosas R, Allia E, Granata R, Baragli A, Muccioli G, et al.
Mol Cell Endocrinol . 2008 Feb; 286(1-2):219-29. PMID: 18248880
Somatostatin (SS) and its synthetic analogs have a role in the treatment of neuroendocrine tumours both in terms of symptoms control and antiproliferative activities. These effects are mediated by five...
3.
Prodam F, Benso A, Gramaglia E, Lucatello B, Riganti F, Lely A, et al.
Neuropeptides . 2007 Dec; 42(1):89-93. PMID: 18061663
Cortistatin (CST), a neuropeptide with high structural homology with somatostatin (SST), binds all SST receptor (SST-R) subtypes but, unlike SST, also shows high binding affinity to ghrelin receptor (GHS-R1a). CST...
4.
Giordano R, Picu A, Bonelli L, Broglio F, Prodam F, Grottoli S, et al.
Eur J Endocrinol . 2007 Sep; 157(4):393-8. PMID: 17893252
Object: Somatostatin (SS) is known to inhibit GH and insulin, while its effect on corticotrope secretion is controversial: inhibition of ACTH secretion by agonists activating somatostatinergic receptors (sst)-2 and sst-5...
5.
Cassoni P, Allia E, Marrocco T, Ghe C, Ghigo E, Muccioli G, et al.
J Endocrinol Invest . 2006 Nov; 29(9):781-90. PMID: 17114908
Ghrelin, a natural GH secretagogue (GHS) acylated peptide, and cortistatin (CST), a natural SRIF-like peptide, interfere with neoplastic growth in different cancers. We tested forty-one lung carcinomas and the H345...
6.
Granata R, Settanni F, Trovato L, Destefanis S, Gallo D, Martinetti M, et al.
J Endocrinol Invest . 2006 Nov; 29(9):RC19-22. PMID: 17114904
Ghrelin is mainly produced by the stomach, although it is expressed in other tissues, including the pancreas. Among its pleiotropic actions, ghrelin prevents the development of diabetes in rats and...
7.
Benso A, Prodam F, Lucatello B, Gramaglia E, Riganti F, Schneider H, et al.
Neuropeptides . 2006 Nov; 41(1):45-9. PMID: 17112585
Acylated ghrelin exerts numerous endocrine and non-endocrine activities via the GH Secretagogue receptor type 1a (GHS-R1a). D-Lys-GHRP-6 has been widely studied in vitro and in vivo in animal studies as...
8.
Broglio F, Prodam F, Riganti F, Muccioli G, Ghigo E
Front Horm Res . 2006 Jul; 35:102-114. PMID: 16809926
Ghrelin, a peptide predominantly produced by the stomach, has been discovered as natural ligand of the GH secretagogue (GHS) receptor type 1a (GHS-R1a), suggesting the existence a new endogenous modulator...
9.
Grottoli S, Gasco V, Broglio F, Baldelli R, Ragazzoni F, Gallenca F, et al.
J Clin Endocrinol Metab . 2006 Feb; 91(4):1595-9. PMID: 16449338
Context: Cortistatin binds all somatostatin receptor subtypes but also has particular central actions; moreover, a specific cortistatin receptor has also been discovered. Objective: We compared the endocrine effects of cortistatin-17...
10.
Sibilia V, Muccioli G, Deghenghi R, Pagani F, De Luca V, Rapetti D, et al.
J Neuroendocrinol . 2006 Jan; 18(2):122-8. PMID: 16420281
Ghrelin, the endogenous ligand of the GH secretagogue receptor (GHS-R) has been previously shown to inhibit gastric acid secretion in pylorus-ligated rats. Two isoforms of GHS-R have been identified: GHS-R(1a)...