G M Pastino
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Explore the profile of G M Pastino including associated specialties, affiliations and a list of published articles.
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6
Citations
43
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Recent Articles
1.
Pastino G, Kousba A, Sultatos L, Flynn E
Regul Toxicol Pharmacol
. 2003 Mar;
37(1):66-72.
PMID: 12662910
An approach for deriving occupational exposure limits (OEL) for pharmaceutical compounds is the application of safety factors to the most appropriate pre-clinical toxicity endpoint or the lowest therapeutic dose (LTD)...
2.
Pastino G, Conolly R
Toxicol Sci
. 2000 Jun;
55(2):256-65.
PMID: 10828256
A portion of ingested ethanol does not reach the systemic circulation in both rats and humans as indicated by higher blood ethanol concentrations following an intravenous administration compared to an...
3.
Pastino G, Yap W, Carroquino M
Environ Health Perspect
. 2000 May;
108 Suppl 2:201-14.
PMID: 10807552
Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments for cancer and...
4.
Pastino G, Flynn E, Sultatos L
Drug Chem Toxicol
. 2000 Mar;
23(1):179-201.
PMID: 10711397
Chronic exposure to excessive ethanol consumption has adverse effects on virtually all organs and tissues in the body, including but not limited to the liver, pancreas, reproductive organs, central nervous...
5.
Pastino G, Asgharian B, Roberts K, Medinsky M, Bond J
Toxicol Appl Pharmacol
. 1997 Jul;
145(1):147-57.
PMID: 9221833
Ethanol is added to unleaded gasoline as an oxygenate to decrease carbon monoxide automobile emissions. This introduces inhalation as a new possible route of environmental exposure to humans. Knowledge of...
6.
Pastino G, Sultatos L, Flynn E
Alcohol Alcohol
. 1996 Jul;
31(4):365-74.
PMID: 8879283
The purpose of the present study was to develop a physiologically based pharmacokinetic (PBPK) model in the mouse and to utilize it to evaluate the relative contribution, if any, of...