G M C Janssen
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Explore the profile of G M C Janssen including associated specialties, affiliations and a list of published articles.
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10
Citations
80
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Recent Articles
1.
Madunic K, Luijkx Y, Mayboroda O, Janssen G, van Veelen P, Strijbis K, et al.
Mol Cell Proteomics
. 2023 Jan;
22(3):100501.
PMID: 36669592
Gut microbiota of the gastrointestinal tract provide health benefits to the human host via bacterial metabolites. Bacterial butyrate has beneficial effects on intestinal homeostasis and is the preferred energy source...
2.
Venema W, Hiddingh S, Janssen G, Ossewaarde-van Norel J, van Loon N, de Boer J, et al.
Clin Immunol
. 2022 Dec;
247:109219.
PMID: 36581221
Background: HLA-A29-positive birdshot chorioretinitis (BCR) is an inflammatory eye disorder that is generally assumed to be caused by an autoimmune response to HLA-A29-presented peptides from retinal arrestin (SAG), yet the...
3.
Tuerlings M, Janssen G, Boone I, van Hoolwerff M, Rodriguez Ruiz A, Houtman E, et al.
Osteoarthritis Cartilage
. 2022 Oct;
31(1):39-48.
PMID: 36208715
Objective: To explore the co-expression network of the osteoarthritis (OA) risk gene WWP2 in articular cartilage and study cartilage characteristics when mimicking the effect of OA risk allele rs1052429-A on...
4.
Lubbers R, Oostindie S, Dijkstra D, Parren P, Verheul M, Abendstein L, et al.
Clin Exp Immunol
. 2019 Dec;
200(1):1-11.
PMID: 31853959
Carbamylation is a post-translational modification that can be detected on a range of proteins, including immunoglobulin (Ig)G, in several clinical conditions. Carbamylated IgG (ca-IgG) was reported to lose its capacity...
5.
Verheul M, van Veelen P, van Delft M, de Ru A, Janssen G, Rispens T, et al.
Autoimmun Rev
. 2017 Dec;
17(2):136-141.
PMID: 29203292
Carbamylation and citrullination are both post-translational modifications against which (auto)antibodies can be detected in sera of rheumatoid arthritis (RA) patients. Carbamylation is the chemical modification of a lysine into a...
6.
van de Kooij B, Rooswinkel R, Kok F, Herrebout M, de Vries E, Paauwe M, et al.
Oncogene
. 2013 Apr;
32(48):5439-48.
PMID: 23563182
Anti-apoptotic Bcl-2 family members can contribute to tumorigenesis and may convey resistance to anti-cancer regimens. Therefore, they are important targets for novel therapeutics, particularly Bcl-2 homology (BH)3 mimetics. Bcl-B (BCL-2-like...
7.
Janssen G, Schwertman P, Wanga T, Tafrechi R, van den Broek P, Raap A
Cell Mol Life Sci
. 2009 Jan;
66(4):721-30.
PMID: 19137259
Cytoplasmic translation is under sophisticated control but how cells adapt its rate to constitutive loss of mitochondrial oxidative phosphorylation is unknown. Here we show that translation is repressed in cells...
8.
Maassen J, t Hart L, Janssen G, Reiling E, Romijn J, Lemkes H
Biochem Soc Trans
. 2006 Oct;
34(Pt 5):819-23.
PMID: 17052206
Multiple pathogenic pathways are able to deregulate glucose homoeostasis leading to diabetes. The 3243A>G mutation in the mtDNA (mitochondrial DNA)-encoded tRNALeu,UUR gene was found by us to be associated with...
9.
Janssen G, Neu A, t Hart L, van de Sande C, Maassen J
Exp Clin Endocrinol Diabetes
. 2006 May;
114(4):168-74.
PMID: 16705548
We have identified two locations with novel multiplasmic length variants in the mitochondrial DNA of a family with diabetes and deafness. At nt568 in the D-loop, the 6-bp polycytidine tract...
10.
Maassen J, Janssen G, Lemkes H
J Endocrinol Invest
. 2002 May;
25(5):477-84.
PMID: 12035948
This review discusses the current insight by which mutations in mitochondrial DNA (mtDNA) contribute to the development of particular disease states with emphasis on diabetes mellitus. Mitochondria are the power...